Biology (BIO)
BIO 103 Contemporary Biology [C3NS]
Credits 3 Grading Basis Graded
An in-depth exploration of selected biological concepts, connected to current, relevant topics and emphasizing an understanding of science as a way of obtaining knowledge. Not available for major or minor credit in biology. May be used for general education credit. May not be used for major credit.
BIO 110 First Year Seminar in Biology
Credits 1 Grading Basis Credit / No Credit
Orientation to the biology and biotechnology majors for first year students, including freshmen and transfer students. Course content includes introduction to the biology/biotechnology curriculum, academic plan building, time management and study skills, stress and anxiety management, campus student resources, undergraduate research, graduate school considerations, and discussion of biology career options. Course provides university elective credit. Not available for biology or biotechnology major credit. Course is offered credit/no-credit.
BIO 140 Foundations of Biology I [C3NS]
Credits 3 Grading Basis Graded
The foundations of the cellular molecules, structures and processes that sustain life in the context of evolution will be explored. Topics will include structure and function; information flow, storage and exchange; pathways and transformations of energy and matter; and systems biology. May be used for general education credit.
BIO 140L Foundations of Biology I Laboratory [C3L]
Credits 1 Grading Basis Graded
Students learn the process of science and the basics of experimental design while building scientific writing skills. Students learn foundational techniques of molecular biology (pipetting, DNA extraction, PCR, gel electrophoresis and basic bioinformatics) in the context of a DNA Barcoding project. Students will leave this course with the preparation needed to design their own independent DNA barcoding projects. May be used for general education credit.
BIO 150 Foundations of Biology II
Credits 3 Grading Basis Graded
Foundations II focuses on the diversity of life, anatomy and physiology of organisms and ecological organization in an evolutionary context. This class will explore structure and function; how information is transmitted; transformations of energy and matter; and how biological units act as integrated systems. The process of science, interdisciplinary approaches and the relevance of biology to society will be addressed.
BIO 150L Foundations of Biology II Laboratory
Credits 1 Grading Basis Graded
Student teams develop and execute semester-long independent research projects using DNA barcoding. Students will learn how to ask scientific questions, explore scientific literature, design scientific studies, analyze and interpret data, and share results using images and scientific writing. This lab emphasizes the development and refinement of research techniques in molecular biology, critical thinking, study design, teamwork and skills in finding, reading and writing scientific literature. Students will leave this course with a deeper understanding of the process of science, an introduction to bioinformatics and molecular biology and improved skills in scientific communication.
BIO 200 Major Biology Elective
Credits 1-4 Grading Basis Student Option
This course is awarded for lower division transfer elective credit applicable toward the biology major or minor. A maximum of four hours may be transferred and used toward the major or minor. Additional hours may be transferred as BIO OOO.
BIO 201 Trelawny Learning Community Seminar I
Credits 1 Grading Basis Graded
The first part of the research skills seminar for first-year students in the Trelawny Learning Community. In addition to lab/field work with faculty or graduate students for 2-3 hours per week, students attend a weekly seminar. Seminar includes research skill and team-building exercises, guest speakers and case studies geared toward a career in science. Faculty and students interact with community members to provide perspectives on the major and research in a scientific network.
Corequisites: Membership in the Trelawny Learning Community.
BIO 202 Trelawny Learning Community Seminar II
Credits 2 Grading Basis Graded
The second part of the research skills seminar for first-year students in the Trelawny Learning Community. Students will have already begun research projects during fall semester, and will continue their projects into spring semester while continuing to build research skills. Students will take part in community, campus and social events and gain experience helping to run a research-based event.
Prerequisites: BIO 201. Corequisites: Membership in the Trelawny Learning Community.
BIO 203 Viral Discovery
Cross-listed with: ISAT 203
Credits 2 Grading Basis Graded
An exploratory laboratory experience, designed for incoming freshmen. Students will learn about the life cycle and ecology of viruses infecting bacteria. Soil samples will be collected, and techniques for isolation and purification of the viruses will be performed by the students. Isolated viruses will be visualized using electron microscopy. The genomic material will be isolated and prepared for nucleic acid sequencing.
BIO 204 Viral Genome and Bioinformatics
Cross-listed with: ISAT 204
Credits 2 Grading Basis Graded
A computer-based laboratory experience, designed for students completing the Viral Discovery course. Students will learn to identify genes in a viral genome, compare the predicted proteins with known proteins in databases, describe the contents of the genome and notate all the relevant information for publication. Students will also research the role of bacteriophages in ecology and evolution.
BIO 226 Introductory Topics in Biology (Variable)
Credits 1-4 Grading Basis Graded
Introductory studies in specific areas of biology. May be repeated for credit when course content changes.
BIO 230 Biology, Gender and Society
Cross-listed with: WGSS 230
Credits 3 Grading Basis Graded
Students in this course will explore the biology of sex and gender and consider their interactions and interrelationships through a lens that considers intersectional identities and societal expectations. Topics include reproductive biology, sexual differentiation, gender development and expression, and the interactions between science and society that inform gendered bodies and practices.
BIO 240 Genetics
Credits 3 Grading Basis Graded
Students will explore how genetic information is utilized throughout the lifetime of the organism. The course focuses on the flow of information and evolutionary principles through the lenses of classical and molecular genetics and genomics.
BIO 240L Genetics Laboratory
Credits 1 Grading Basis Graded
Students will explore both classic and molecular genetic techniques using genetic model organisms. Additionally, students will learn how to analyze large data sets using widely available data bases, data analysis programs and introductory coding.
BIO 245 General Microbiology
Credits 3 Grading Basis Graded
A study of the microorganisms, their significance, evolution, structure and function, genetics and the systems in which they exist.
BIO 245L General Microbiology Laboratory
Credits 1 Grading Basis Graded
This laboratory course is designed to complement and supplement the BIO 245 lecture course.
BIO 246 Microbiology Seminar
Credits 1 Grading Basis Graded
Seminars, readings and discussions of the primary scientific literature with a focus on the current research in the field of microbiology.
BIO 250 Quantitative Ecology and Evolution
Credits 3 Grading Basis Graded
Students will use an interactive e-text application to explore the changing natural world through modeling and simulation in a discovery-based classroom environment. Throughout every unit, the relationship among evolution, ecology and the environment are woven together using current research from primary literature. Evolution is explored in many relevant contexts, including artificial and natural selection of GMOs and of antibiotic resistance. In a module covering the evolution of decision making, students will learn quantitative approaches to game theory, optimal foraging and sexual selection. An understanding of population ecology and evolution is gained as students manipulate models to understand competition and predator-prey dynamics with real case studies of both microbes and endangered species. Climate change is discussed through the use of mathematical models and current and historical data.
BIO 250L Quantitative Ecology and Evolution Laboratory
Credits 1 Grading Basis Graded
Hands-on laboratory and field-based experiences which emphasize experimental design and both statistical and quantitative analyses, with an emphasis on oral and written professional communication.
BIO 260 Foundations of Human Anatomy and Physiology
Credits 4 Grading Basis Graded
An introduction to anatomy (structure) and physiology (function) of the human body and its organ systems which will provide a strong foundation in the relationship of human structure and function. BIO 260 is designed to meet the Virginia Science Content educational guidelines for A&P. Credit may not be earned in both BIO 260 and BIO 270/BIO 270L and BIO 290/BIO 290L.
BIO 270 Human Physiology [C3NS]
Credits 3 Grading Basis Graded
An introduction to basic physiological principles using humans as the primary organism. Physiological adaptations will be examined at the molecular through organismal levels. Intended for students in health-related fields and The Natural World of the general education program. Not available for biology or biotechnology major credit. Credit for BIO 270/BIO 270L and BIO 290/BIO 290L may be transferred together to JMU only when transferable credits for two semesters of anatomy and physiology (I & II) are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO.
BIO 270L Human Physiology Laboratory [C3L]
Credits 1 Grading Basis Graded
This laboratory course is conducted to directly observe how the body's systems work and how scientific knowledge is accumulated in conjunction with the BIO 270 lecture course. Organizational and leadership skills are promoted by individual and group laboratory activities. Credit for BIO 270L and BIO 290L may be transferred together to JMU only when transferrable credits for two semesters of anatomy and physiology (I & II) lab are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO. May be used for general education credit.
BIO 290 Human Anatomy
Credits 3 Grading Basis Graded
A regionally based study of the human body. Emphasis on major body structures and function is reinforced through hands-on examination of prosected cadaver specimens and other anatomical resources during the prerequisite or corequisite laboratory experience. Credit for BIO 270/BIO 270L and BIO 290/BIO 290L; may be transferred together to JMU only when transferrable credits for two semesters of Anatomy & Physiology (I & II) are completed at the same institution. A single semester, or courses from different institutions, transfer as BIO OOO.
BIO 290L Human Anatomy Laboratory
Credits 1 Grading Basis Graded
A regionally-based study of the human body. Emphasis on major body structures and function through hands-on examination of prosected cadaver specimens and other anatomical resources. Credit for BIO 270L and BIO 290L may be transferred together to JMU only when transferrable credits for two semesters of anatomy and physiology (I & II) lab are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO.
BIO 301 Introductory Neuroscience
Credits 3 Grading Basis Graded
This course will examine molecular control of neuronal function. Topics include the structure and function of neuronal excitability, chemical and contact mediated neuronal communication, developing and regenerating nervous systems, sensation and perception, learning and memory formation, repair from neuronal damage, and the neuronal pathways of sensation and motor control. In the context of these subjects, we will review the neuronal alterations that cause some common brain diseases.
BIO 302 Bioethics for Biologists
Credits 3 Grading Basis Graded
In this primarily discussion-based class, students will develop an understanding of the impact of biological and medical advances on society and why biologists and citizens must be aware of the accompanying bioethical issues. The development of the bioethics field will be explored, and biological, medical and technological advances will be described. Students will explore these topics with appropriate bioethics readings, short writing assignments synopsizing the readings, group discussions and in-class presentations selected by the students.
Prerequisites: BIO 140 or permission of the instructor.
BIO 304 Cell and Molecular Biology
Credits 3 Grading Basis Graded
Students will develop a deeper understanding of the molecular mechanisms employed by procaryotic and eucaryotic cells. Topics will include (1) macromolecular structure and function and how macromolecules coordinate to maintain life, (2) molecular mechanisms that regulate the synthesis and flow of genetic information and (3) molecular aspects of homeostasis, bioenergetics and cell signaling.
BIO 310 Marine Biology
Credits 3 Grading Basis Graded
An exploration of the functional biology, ecology, and biodiversity of marine organisms. Students will be provided with a general understanding of how the ocean works and how marine organisms operate within their environment. The diversity of marine organisms in the open sea and benthos will be surveyed and a discussion of the numerous threats impacting various marine ecosystems will also be included.
BIO 316 Animal Development
Credits 3 Grading Basis Graded
This course integrates cell and molecular biology and genetics to understand the processes and mechanisms underlying body plan formation and organ formation in vertebrate animals and insects. The course additionally covers the development of muscle, skeleton and nervous tissues, the postembryonic phenomena of growth, metamorphosis and regeneration, and the developmental basis of evolutionary changes in animal anatomy.
BIO 318 Experimental Vertebrate Development
Credits 2 Grading Basis Graded
Students design and carry out independent research projects on different aspects of frog or chick development. Skills include manipulating live embryos, raising embryos and larvae from eggs, using wax histology to make microscope slides, immunohistochemistry, 3D reconstruction and morphometry-based analyses, and filming animal behavior. Projects are hypothesis-driven and investigate patterns, mechanisms and behaviors involved in the development of skeleton, lungs, tails, limbs and other organs.
BIO 320 Comparative Anatomy of Vertebrates
Credits 4 Grading Basis Graded
This course explores the anatomical evolution of vertebrates, including the phylogenetic, developmental and functional significance of structures and systems across the vertebrate family tree. Students will gain key competencies in tree-thinking, specimen dissection, comparing and conveying anatomical form, and evaluating and synthesizing information to generate hypotheses and propose future directions in the field of comparative vertebrate anatomy.
BIO 324 Human Genetics
Credits 3 Grading Basis Graded
An intermediate genetics course with an emphasis on human biology. Topics include cytogenetics, pedigree analysis, quantitative traits, mutation, epigenetics, genomics and ethical issues raised by developing technologies.
BIO 325 Medical Parasitology
Credits 3 Grading Basis Graded
This course covers the study and medical implications of parasites that infect humans. Class activities will emphasize parasite morphology, modes of transmission, mechanisms of host entry and infection, niche selection, life cycles, pathogenesis, diagnosis, and treatment and control.
BIO 326 Intermediate Topics in Biology
Credits 1-4 Grading Basis Graded
This course covers specified areas of biology taught at the 300 level. May be repeated for credit when course content changes. See MyMadison for prerequisites for specific topics.
BIO 327 Biological Illustration
Credits 3 Grading Basis Graded
Students will consider how the skills of visual art are used in the dissemination of data. Students will learn how to sketch, paint and digitally illustrate microscopic specimens, live and dead plants and animals, bones, cellular processes and scientific methodology. Students will be instructed in different illustration techniques and be encouraged to find their preferred medium to produce a portfolio of images. The course content can be modified to reflect the interests/needs of the students. Students are responsible for obtaining all materials required for completing exercises and projects. Students may also obtain their own biological subjects.
BIO 330 Evolution
Credits 3 Grading Basis Graded
This course provides an introduction to evolutionary biology, including evidence for evolution, natural selection, genetic drift, sexual selection, phylogenetics, genome evolution, speciation, macroevolution, the history of life on Earth and the evolution of infectious disease.
BIO 340 Morphology and Anatomy of Vascular Plants
Credits 4 Grading Basis Graded
A detailed study of the comparative morphology and anatomy of tracheophytes.
BIO 342 Mathematical Models in Biology
Cross-listed with: MATH 342
Credits 3 Grading Basis Graded
Introduction to dynamical models (discrete and continuous time) applied to biology. Tools of mathematical analysis from linear and nonlinear dynamics will be taught, including stability analysis of equilibrium, as well as appropriate use of software packages. Emphasis will be on model development and interpretation in the context of applications, including effective written and oral presentation.
BIO 346 Laboratory in Bacterial Pathogenomics
Credits 2 Grading Basis Graded
A course-based-research laboratory course. Students isolate pathogenic bacteria from environmental samples, identify and characterize them, and sequence their whole genomes. Students learn the basics of microbial genomics, including genome assembly, annotation and comparative genomics methods to study mobile genetic elements, virulence, antibiotic resistance, etc. They also learn how these methods are used in the epidemiological tracking of pathogens.
BIO 348 Medical Microbiology
Credits 3 Grading Basis Graded
Students will learn about microorganisms of medical importance, mainly bacteria and viruses. Key topics for each organism include general cell structure, unique structures/functions, epidemiology of the disease that the organism causes, mechanisms of pathogenesis, isolation and identification of the organism, and treatment options.
BIO 348L Medical Microbiology Laboratory
Credits 1 Grading Basis Graded
This laboratory course consists of a series of case studies that require the students to identify the likely causative agent of the symptoms described in the case study.
BIO 350 Paleobiology
Cross-listed with: GEOL 350
Credits 4 Grading Basis Graded
The evolution and ecological structure of the biosphere from the origin of life to the present, emphasizing the evolution and paleobiology of animal life as shown by the fossil record. Lectures discuss methods used to interpret the fossil record and cover topics such as phylogeny and systematics, functional morphology, biostratigraphy, paleoecology, evolution and extinction. Laboratories focus on the major groups of invertebrates that are common in the geologic record.
BIO 354 Global Climate Change and Life: Ecological and Biological Impacts of Climate Variability
Credits 4 Grading Basis Graded
Global climate change is important to the distribution, diversity, health and survival of organisms. The biota have changed through evolution in part as a response to selection pressures from these variations. Living things can also adjust to change through phenotypic flexibility. This course examines, in a seminar/discussion format, the potential ecological impacts of past and current patterns of climate alteration on organisms.
BIO 357 Galápagos Islands: Biodiversity and Conservation
Credits 3 Grading Basis Graded
A detailed study of the biodiversity, conservation, biogeography and natural history of the Galápagos Islands.
BIO 360 Plant Biology
Credits 3 Grading Basis Graded
This course is an introduction to the biology of plants including evolution, diversity, form and function, ecology, and biotechnology.
BIO 360L Plant Biology Laboratory
Credits 1 Grading Basis Graded
An exploration of plant structure, function, evolution and biological diversity.
BIO 361 Biochemistry I
Cross-listed with: CHEM 361
Credits 3 Grading Basis Graded
An introduction to the molecules and chemical reactions of living systems. Structure and function of important classes of biomolecules are explored and the relationship of structure to function is stressed. Basic metabolic sequences are discussed.
Prerequisites: CHEM 241 and permission of the instructor.
BIO 364 Human Uses of Plants
Credits 3 Grading Basis Graded
A survey of past, present and future uses of plants with emphasis on economically important plant families. Issues of cultivated plant origins, biodiversity and germplasm preservation are considered.
BIO 364L Laboratory in Human Uses of Plants
Credits 1 Grading Basis Graded
An investigative examination of plants and their constituents with an emphasis on their physiological ecology, adaptations and economic utilization by humans.
BIO 370 Human and Animal Physiology
Credits 4 Grading Basis Graded
Design and function of cellular and organ physiology will be explored in both humans and other animals. The course will begin by using an organ system approach to introduce basic physiological principles and develop understanding of physiological processes which requires the integration of multiple organ systems functioning. The course is intended for biology majors and minors. Class activities will emphasize problem-solving and collaborative and independent learning. The laboratories will utilize computer simulations and animal/human experiments to examine principles of both physiology and scientific investigation.
BIO 375 Sensation and Perception
Cross-listed with: PSYC 375
Credits 3 Grading Basis Graded
This course explores the nature and development of human sensory capabilities and processing, and how these affect perception of the environment. A potential list of the variety of systems reviewed includes hearing, vision, smell, taste and touch/pain, as well as phenomena such as the perception of balance.
BIO 380 Advanced Microbiology Laboratory Techniques
Credits 1 Grading Basis Graded
This course will focus primarily on advanced microbiology laboratory techniques. The techniques may include microcopy, staining, autoclave use and preparation of media, maintenance of stock cultures, and spectroscopy. This course will help prepare students for research and advanced microbiology laboratory courses.
BIO 385 Biopsychology
Cross-listed with: PSYC 385
Credits 3 Grading Basis Graded
This course is a survey of the neurological and chemical mechanisms which control behavior. Students will examine the brain and how it processes sensation, perception, cognition, movement, motivation, learning, memory and other behavioral processes of interest to psychologists.
BIO 386 Field Botany
Credits 4 Grading Basis Graded
An in-depth survey of vascular plants in the field with emphasis on identification, diversity of form and function, and ecology. Laboratory topics will include techniques for sampling plant communities, identifying local flora and preserving botanical materials.
BIO 387 Environmental Microbiology
Credits 3 Grading Basis Graded
An examination of microbial diversity in the environment and the functional role of microbes in ecosystems around the world.
BIO 387L Environmental Microbiology Laboratory
Credits 1 Grading Basis Graded
This course is a field-based investigative lab experience exploring the structure and function of microbial communities and applications of microbiology.
BIO 395 Comparative Animal Behavior
Cross-listed with: PSYC 395
Credits 3 Grading Basis Graded
This course covers aspects of the development, function and evolution of the behavior of nonhuman animals. Topics covered include intraspecies communication, feeding, aggression, territoriality, reproductive behavior and social behavior.
BIO 400 Geology and Ecology of the Bahamas
Credits 3 Grading Basis Graded
This course explores the geology and ecology of the shallow-water marine environment by examining the preeminent modern example, the Bahamas platform. The Bahamas provide an excellent model for understanding modern and ancient carbonate and reef deposits and a variety of terrestrial/aquatic habitats. Biological processes are responsible for many of the geological features of the Bahamas, so the course considers the biology/ecology of marine organisms in addition to geological topics.
BIO 402 Forest Ecology
Cross-listed with: BIO 502
Credits 4 Grading Basis Graded
A study of the function, structure and composition of forested ecosystems. The effect of physical geography on the distribution of forest communities will be explored. Issues of forest management and restoration will also be considered. Field laboratory topics will include dendrology and sampling techniques within different forest successional stages.
BIO 404 Evolutionary Analysis
Credits 3 Grading Basis Graded
An examination of the place of theoretical thought in biology. The concepts of phylogenetic relationships and the mechanisms of organic change as expressed through the principles of organic evolution will be stressed.
BIO 405 Vertebrate Paleontology
Cross-listed with: GEOL 405
Credits 3 Grading Basis Graded
A study of the origin and evolution of the vertebrates. Emphasis will be on understanding how the processes of Earth evolution and biological evolution have interacted through time to produce a coherent picture of vertebrate history.
BIO 410 Advanced Human Anatomy
Credits 3 Grading Basis Graded
An advanced study of topics in human anatomy using dissection techniques.
BIO 412 Mammalogy
Credits 4 Grading Basis Graded
An introduction to the study of mammals, incorporating evolutionary history, general physiology, reproductive biology, systematics, ecology, wildlife management and behavior, followed by review of mammalian taxonomic orders. Lecture is reinforced with laboratory and field experience. Completion of BIO 320 recommended.
BIO 415 Neuroanatomy and Neurogenic Communication Disorders
Cross-listed with: CSD 415
Credits 3 Grading Basis Graded
This course is an introduction to neuroanatomy with emphasis on neurogenic communication disorders.
Prerequisites: CSD 208 or permission of the instructor.
BIO 418 Conservation Biology
Credits 3 Grading Basis Graded
Conservation biology is the study and management of biodiversity with the aim of protecting species, their habitats and ecosystems from excessive rates of extinction. The course will focus on ecological theory, population dynamics, conservation and restoration strategies, and ethical questions for conservation. The course will also teach students to analyze open-ended questions via case studies.
BIO 419 Animals and their Environments
Credits 4 Grading Basis Graded
This course provides an exploration of terrestrial and aquatic animal ecology with a focus on the ecology of vertebrates in a rapidly changing world. Students will investigate how animal ecology is shaped by the environment and how animals in turn shape their biotic and abiotic environments. Lectures will be composed of small group work to synthesize information from primary literature readings and other sources. Field laboratory topics will involve travel to various local ecosystems. Students will build skills with techniques used in ecological studies focused on various local taxa and ecological communities. Students will build transferable skills in experimental design, field techniques, problem solving, data management, manipulation, visualization and analysis via activities embedded in both lecture and laboratory throughout the course. Students will use these skills to collaboratively design, complete and present course-based field research projects.
BIO 425 Immunology
Credits 3 Grading Basis Graded
This course studies the molecular and cellular basis of the immune system. Topics include the properties of antigens and immunoglobulins, the development and regulation of humoral and cell-mediated immunity, resistance and immunization to infectious diseases, allergies and autoimmune and immunodeficiency disorders.
BIO 425L Immunology Laboratory
Credits 1 Grading Basis Graded
This course will introduce students to the theory and application of many of the methods currently used in clinical and research immunology. Laboratory exercises will focus on methods for identifying, quantifying and assessing functional activities of immune cells and molecules. Students will gain experience using experimental animals and in animal cell culture techniques.
BIO 426 Topics in Biology
Credits 1-4 Grading Basis Graded
Specified areas of biology. May be repeated for credit when course content changes. See MyMadison for prerequisites for specific topics.
BIO 427 Topics in Biology with Laboratory
Credits 1-4 Grading Basis Graded
BIO 430 Ornithology: Research and Current Advances
Credits 4 Grading Basis Graded
Students will design and engage in course-based research projects using modern approaches to ornithology. Classes will investigate current primary literature on ornithological research, recent technological advances and conservation. Lectures and labs will explore the biodiversity of birds, identification by sight and sound, and the ecology, evolution, physiology and behavior of birds. Labs will involve fieldwork, data collection and workshops such as sound analysis and geographic tracking. BIO 430 will be taught concurrently with BIO 530.
BIO 432 Light Microscopy
Cross-listed with: BIO 532
Credits 4 Grading Basis Graded
This course covers the principles behind light microscopy, from the properties of light to the latest technologies in microscopy. Students will get hands-on experience with the different kinds of microscopes, including the confocal microscope. The course also covers fluorescent probes, advanced fluorescence techniques, digital imaging, methods of quantification and figure preparation for publication, with an emphasis on biological applications.
BIO 443 Understanding Techniques in Neuroscience
Credits 3 Grading Basis Graded
A writing-intensive introduction to basic neurobiological processes that draws from molecular biology, genetics, biochemistry, behavioral biology, electrophysiology, pharmacology, computer science and optics. Topics will include both classic and state-of-the-art techniques. Special emphasis will be placed on framing techniques as tools to answer basic scientific questions in neuroscience. BIO 443 is taught concurrently with BIO 543. Credit may not be earned in both BIO 443 and BIO 543.
BIO 444 Virology
Credits 3 Grading Basis Graded
BIO 445 Neurobiology
Credits 4 Grading Basis Graded
Molecular, cellular and network mechanisms underlying behavior will be studied using problem-solving, discussion, lecture and critical reading of the primary literature. Similarities and differences between nervous systems and computers will be explored. Laboratories will utilize contemporary electrophysiology and computer simulation to examine the neurobiology of simple animal model systems.
BIO 446 Experimental Neurobiology
Cross-listed with: BIO 546
Credits 4 Grading Basis Graded
The experimental basis of neurobiology will be explored in invertebrates and humans using modern neurobiological techniques, such as extracellular, intracellular, electromyogram and voltage clamp recording. The course will revolve primarily around the laboratory activities, with the single lecture section designed to support the laboratory. Students will be expected to complete a project that involves developing a new experimental approach or model system.
BIO 447 Evolution and Ecology of Infectious Disease
Cross-listed with: BIO 547
Credits 3 Grading Basis Graded
An introduction to the evolution and ecology of pathogenic microorganisms, with an emphasis on the bacteria. Emphasis will be placed on the study, discussion and critique of scientific literature, as well as formal presentation of scientific information and data.
BIO 448 Developmental Neurobiology
Credits 3 Grading Basis Graded
Exploration of molecular and cellular mechanisms that determine neuronal identity, migration, synaptogenesis, synaptic plasticity and neural systems organization. Critical and intensive evaluation and communication of primary literature.
BIO 449 Insect Ecology
Cross-listed with: BIO 549
Credits 4 Grading Basis Graded
An overview of insect ecology from an evolutionary perspective, focusing on the processes that affect the diversity, distribution and abundance of insects in natural and managed ecosystems. The role of insects as model systems in understanding ecological and evolutionary principles is included, and current literature in the field is highlighted. Field surveys and experiments are emphasized, including general insect collection and identification.
BIO 451 Current Topics in Human Development and Evolution
Cross-listed with: BIO 551
Credits 3 Grading Basis Graded
Discussion-based course on the developmental changes involved in our evolution from ape-like ancestors; using the science of cloning and embryonic stem cells to prolong human life; the evolutionary theory of aging; the genetic conflict theory of human pregnancy; the developmental basis of variation in human sexuality; and the direct effects of environment on modern human development and evolution.
BIO 454 Introduction to Biometrics
Cross-listed with: MATH 354
Credits 4 Grading Basis Graded
This course discusses the role of statistics in biological research and interpretation of biological phenomena. The course will cover topics of sampling, correlation, regression analysis, tests of hypotheses, commonly observed distributions in natural populations, nonparametric tests, goodness-of-fit tests and ANOVA. In order to fully comprehend the statistical analysis of those publications, students will review approximately half a dozen publications from different fields of biology.
BIO 456 Ecological Models and Data
Credits 4 Grading Basis Graded
Emerging issues in health and environmental sciences require an understanding of how to make inferences and decisions in the face of limited data and uncertainty. In the past few decades, advances in computational sciences have opened new ways of using and interpreting data. These advances are fundamentally changing how biologists approach statistics. This course introduces students to the principles of probability and likelihood that underpin these growing areas of statistics, and teaches students how to apply these principles to statistical computing. Examples come from ecological models and data and reflect general principles of working with discrete and continuous data, maximum likelihood and Bayesian estimation techniques, and using fundamental principles of probability to build and interpret mixed and mixture models. Work will be done using the open-source statistics program, R, and exercises will emphasize building skills by working with peers and by trial-and-error, both of which are key features of the open-source computing community.
BIO 457 Biological Applications of Geographic Information Systems
Credits 4 Grading Basis Graded
This course will explore the various ways that geographic information systems (GIS) can be used to answer biological questions. Students will use GIS software to study applications in ecology, conservation biology, and environmental biology. No prior GIS experience required.
BIO 459 Freshwater Ecology
Credits 4 Grading Basis Graded
Functional relationships and productivity of freshwater communities are examined as they are affected by their physical, chemical and biotic environment. Organisms inhabiting lakes, ponds, rivers, streams and estuaries are studied at the population, community and ecosystem levels.
BIO 460 Plant Biotechnology
Cross-listed with: BIO 560
Credits 4 Grading Basis Graded
Theory and practice of growing isolated plant cells, tissues and organs.
BIO 467 Human Cardiovascular Physiology
Credits 3 Grading Basis Graded
An in-depth look at the human cardiovascular system by means of advanced physiology with clinical applications and case-based learning. While the course is focused on the human heart and blood vessels, other body systems will be discussed in the context of their association and integration with the cardiovascular system.
BIO 468 Endocrinology
Cross-listed with: BIO 568
Credits 3 Grading Basis Graded
Study of endocrine organs and mechanisms of action of hormones. Students will be involved in interactive lectures and team-based learning activities to understand endocrine functions and disorders.
BIO 472 Human Metabolism
Credits 3 Grading Basis Graded
This course will focus on the cellular physiological mechanisms responsible for regulation of normal human metabolism and place them in the context of the development of chronic disease processes.
BIO 474 Reproductive Physiology
Credits 3 Grading Basis Graded
This is an advanced-level vertebrate physiology course in which students will learn reproductive anatomy, physiology, development and behavior of a variety of organisms with humans serving as the foundational species. Innate and manipulated physiological mechanisms controlling reproduction will be examined at the molecular through organismal levels. Intended for students in organismal biology and health-related fields.
BIO 477 The Genetics of Cancer
Cross-listed with: BIO 577
Credits 3 Grading Basis Graded
Exploration of the genetic and epigenetic factors that drive the evolution of cancer cells, taking into account both inherited and environmental contributions to this process. The cellular mechanisms debilitated or subverted during cancer development will be studied, and student teams will demonstrate their understanding of the material through the diagnosis, genetic characterization and treatment of a hypothetical cancer patient.
BIO 478 Aging and Neurodegeneration
Credits 3 Grading Basis Graded
This course will examine cellular mechanisms, genetics and environmental factors that underlie the onset and progression of age-related neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's and Amyotrophic lateral sclerosis (ALS). This course will build on students' foundational knowledge of cell function, apoptosis and genetics to understand mechanisms that initiate and drive the proliferation neuronal cell death in age-related neurodegenerative diseases. In this course, students also study advancements in research and technology that have led to improved diagnosis and treatment of neurodegenerative disease.
BIO 480 Advanced Molecular Biology
Credits 3 Grading Basis Graded
This course is a study of the history, basic principles and ethical considerations in the field of molecular biology. Students will learn about the structure and function of nucleic acids, proteins and other cellular macromolecules to appreciate the power and limitations of current resources and knowledge.
BIO 480L Advanced Molecular Biology Lab
Credits 1 Grading Basis Graded
This course is a study of the applied practices in the field of molecular biology. Students will participate in hands-on wet bench and computational experiments analyzing nucleic acids, proteins and other cellular macromolecules to appreciate the power and limitations of current resources and knowledge.
BIO 481 Genomics
Cross-listed with: BIO 581
Credits 4 Grading Basis Graded
This advanced biology course is designed for students to learn about the structure and function of genomes, to develop facility in web-based tools and resources, and to appreciate the power and limitations of current resources and knowledge. Focus is on the biological questions that genomics can help to answer. Laboratory exercises will be sequencing and analyzing genomic DNA.
BIO 482 Human Histology
Credits 4 Grading Basis Graded
Students will examine microscopic structure of cells, tissues and major organ systems of the body. Basic anatomical and physiological function is presented to emphasize the histological significance of the examined organ systems.
BIO 483 Bioinformatics
Cross-listed with: BIO 583
Credits 4 Grading Basis Graded
Focuses on building databases and computer programs to manage and analyze biological sequence data, and secondarily on theoretical aspects. The overall objective is to learn current information about the intersection of information science and biology, to develop facility in the many web-based tools and resources for further studies and research in genomics/bioinformatics, and to appreciate the power and limitations of current resources and knowledge.
BIO 484 Aquatic Microbiology
Credits 3 Grading Basis Graded
This research-embedded course will introduce students to the techniques and experimental design currently used in aquatic microbial ecology through both literature and laboratory procedures. Students will participate in projects that are currently a component of the instructor's research program. BIO 484 will be taught concurrently with BIO 584.
BIO 486 Systematics of Vascular Plants
Credits 4 Grading Basis Graded
Study of systematic theory and an overview of the classification and evolution of higher plants, with particular attention to flowering plant families. Techniques for plant identification and collection and for construction of phylogenies will be taught in lab.
BIO 489 Topics in Science Pedagogical Content Knowledge
Cross-listed with: MSSE 495
Credits 2 Grading Basis Graded
Contributes to the further development of pre-service secondary science teachers' pedagogical content knowledge. Students will engage in education research to gain experience and develop instructional practices relevant to the Virginia Standards of Learning. To supplement their understanding of scientific concepts and the process of science, the focus will be on the nature of science encompassing literature from the history, philosophy, and sociology of science.
BIO 490 Mechanics of Animal Movement
Credits 4 Grading Basis Graded
The interactions of organisms with their physical environment. Concepts from fluid and solid mechanics are applied to biological form and function.
BIO 491 Scientific Writing, Presentation and Critical Thinking
Credits 2 Grading Basis Credit / No Credit
A discussion-based course for the development of the fundamental thinking, writing and presentation skills necessary to be a successful researcher. This course is required for all Biology Track I and II Honors students in their sophomore year, and is strongly recommended for all Biology majors who are intending to do research. Offered as credit/no credit only.
BIO 492 Mentored Biology Course Assistant
Credits 0-1 Grading Basis Credit / No Credit
Students are trained in the support and function of undergraduate biology courses. Students must contact and make arrangements with the supervising instructor in the term prior to registration. May be repeated when course content and/or student responsibilities within the course change. Offered as credit/no credit only.
Prerequisites: GPA of 2.5 or higher and permission of the instructor.
BIO 493 Pre-Veterinary Student Internship
Credits 2 Grading Basis Credit / No Credit
Students are supervised by veterinarians and lab technicians in diagnostic lab activities at a regional animal health laboratory. A proposal and final presentation are required. Enrollment is limited to 1-2 individuals per term and students are advised to contact the Pre-Veterinary coordinator to be waitlisted. Offered as credit/no credit only.
BIO 494 Internship in Biology
Credits 1-2 Grading Basis Credit / No Credit
Students participate in research or applied biology outside of this university. Students must contact and obtain approval of a supervising instructor at the off campus location and with the department internship coordinator in the term prior to registration. A proposal must be approved prior to registration and a final paper or presentation will be completed. Offered as credit/no credit only.
Prerequisites: Biology or biotechnology major with a minimum of eight biology credit hours and a GPA of 2.5 or greater.
BIO 496 Biological Research
Credits 0-1 Grading Basis Credit / No Credit
Students pursue a lab or field research project in a selected area of biology with a faculty research mentor. This could be research techniques (lab or field), literature review or both. Students must contact and make arrangements with a supervising instructor in the term prior to registration. This course may be repeated, and up to 2 credits may be used to partially satisfy one upper level laboratory requirement for the biology major. This course is offered as credit/no-credit only.
Prerequisites: GPA of 2.5 or greater.
BIO 497 Advanced Biological Research
Credits 0-1 Grading Basis Credit / No Credit
Students pursue a lab or field research project in a selected area of biology with a faculty research mentor. Students must contact and make arrangements with a supervising instructor in the term prior to registration. Students must complete a proposal or form of scientific communication by the end of the semester, such as a conference presentation, Biosymposium presentation, lab presentation or research paper, at the discretion of the instructor. This course may be repeated, and may be used towards the combined 3 credits of research to satisfy one upper level lab requirement for the biology major. This course is offered as credit/no credit only.
Prerequisites: GPA of 2.5 or higher and permission of the instructor.
BIO 499A Senior Project
Credits 2 Grading Basis Graded
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
BIO 499B Senior Project
Credits 2 Grading Basis Graded
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
BIO 499C Senior Project
Credits 2 Grading Basis Graded
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
