Biology (BIO)

BIO 103  Contemporary Biology [C3NS]  
Credits 3   Grading Basis Graded  
An in-depth exploration of selected biological concepts, connected to current, relevant topics and emphasizing an understanding of science as a way of obtaining knowledge. Not available for major or minor credit in biology. May be used for general education credit. May not be used for major credit.
BIO 110  First Year Seminar in Biology  
Credits 1   Grading Basis Credit / No Credit  
Orientation to the biology and biotechnology majors for first year students, including freshmen and transfer students. Course content includes introduction to the biology/biotechnology curriculum, academic plan building, time management and study skills, stress and anxiety management, campus student resources, undergraduate research, graduate school considerations, and discussion of biology career options. Course provides university elective credit. Not available for biology or biotechnology major credit. Course is offered credit/no-credit.
BIO 140  Foundations of Biology I [C3NS]  
Credits 3   Grading Basis Graded  
The foundations of the cellular molecules, structures and processes that sustain life in the context of evolution will be explored. Topics will include structure and function; information flow, storage and exchange; pathways and transformations of energy and matter; and systems biology. May be used for general education credit.
Prerequisites: BIO 140L. Corequisites: BIO 140L.
BIO 140L  Foundations of Biology I Laboratory [C3L]  
Credits 1   Grading Basis Graded  
Students learn the process of science and the basics of experimental design while building scientific writing skills. Students learn foundational techniques of molecular biology (pipetting, DNA extraction, PCR, gel electrophoresis and basic bioinformatics) in the context of a DNA Barcoding project. Students will leave this course with the preparation needed to design their own independent DNA barcoding projects. May be used for general education credit.
Prerequisites: BIO 140. Corequisites: BIO 140.
BIO 150  Foundations of Biology II  
Credits 3   Grading Basis Graded  
Foundations II focuses on the diversity of life, anatomy and physiology of organisms and ecological organization in an evolutionary context. This class will explore structure and function; how information is transmitted; transformations of energy and matter; and how biological units act as integrated systems. The process of science, interdisciplinary approaches and the relevance of biology to society will be addressed.
Prerequisites: BIO 150L and minimum grade of "C-" in BIO 140 and BIO 140L. Corequisites: BIO 150L.
BIO 150L  Foundations of Biology II Laboratory  
Credits 1   Grading Basis Graded  
Student teams develop and execute semester-long independent research projects using DNA barcoding. Students will learn how to ask scientific questions, explore scientific literature, design scientific studies, analyze and interpret data, and share results using images and scientific writing. This lab emphasizes the development and refinement of research techniques in molecular biology, critical thinking, study design, teamwork and skills in finding, reading and writing scientific literature. Students will leave this course with a deeper understanding of the process of science, an introduction to bioinformatics and molecular biology and improved skills in scientific communication.
Prerequisites: BIO 150 and minimum grade of "C-" in BIO 140 and BIO 140L. Corequisites: BIO 150.
BIO 200  Major Biology Elective  
Credits 1-4   Grading Basis Student Option  
This course is awarded for lower division transfer elective credit applicable toward the biology major or minor. A maximum of four hours may be transferred and used toward the major or minor. Additional hours may be transferred as BIO OOO.
BIO 201  Trelawny Learning Community Seminar I  
Credits 1   Grading Basis Graded  
The first part of the research skills seminar for first-year students in the Trelawny Learning Community. In addition to lab/field work with faculty or graduate students for 2-3 hours per week, students attend a weekly seminar. Seminar includes research skill and team-building exercises, guest speakers and case studies geared toward a career in science. Faculty and students interact with community members to provide perspectives on the major and research in a scientific network.
Corequisites: Membership in the Trelawny Learning Community.
BIO 202  Trelawny Learning Community Seminar II  
Credits 2   Grading Basis Graded  
The second part of the research skills seminar for first-year students in the Trelawny Learning Community. Students will have already begun research projects during fall semester, and will continue their projects into spring semester while continuing to build research skills. Students will take part in community, campus and social events and gain experience helping to run a research-based event.
Prerequisites: BIO 201. Corequisites: Membership in the Trelawny Learning Community.
BIO 203  Viral Discovery  
Cross-listed with: ISAT 203  
Credits 2   Grading Basis Graded  
An exploratory laboratory experience, designed for incoming freshmen. Students will learn about the life cycle and ecology of viruses infecting bacteria. Soil samples will be collected, and techniques for isolation and purification of the viruses will be performed by the students. Isolated viruses will be visualized using electron microscopy. The genomic material will be isolated and prepared for nucleic acid sequencing.
BIO 204  Viral Genome and Bioinformatics  
Cross-listed with: ISAT 204  
Credits 2   Grading Basis Graded  
A computer-based laboratory experience, designed for students completing the Viral Discovery course. Students will learn to identify genes in a viral genome, compare the predicted proteins with known proteins in databases, describe the contents of the genome and notate all the relevant information for publication. Students will also research the role of bacteriophages in ecology and evolution.
Prerequisites: ISAT 203 or BIO 203.
BIO 226  Introductory Topics in Biology (Variable)  
Credits 1-4   Grading Basis Graded  
Introductory studies in specific areas of biology. May be repeated for credit when course content changes.
BIO 230  Biology, Gender and Society  
Cross-listed with: WGSS 230  
Credits 3   Grading Basis Graded  
Students in this course will explore the biology of sex and gender and consider their interactions and interrelationships through a lens that considers intersectional identities and societal expectations. Topics include reproductive biology, sexual differentiation, gender development and expression, and the interactions between science and society that inform gendered bodies and practices.
Prerequisites: Either BIO 103, BIO 150, CHEM 120, CHEM 131, GEOL 110, GEOL 210, or ISAT 112.
BIO 240  Genetics  
Credits 3   Grading Basis Graded  
Students will explore how genetic information is utilized throughout the lifetime of the organism. The course focuses on the flow of information and evolutionary principles through the lenses of classical and molecular genetics and genomics.
Prerequisites: BIO 240L and minimum grade of "C-" in BIO 150 and BIO 150L. Corequisites: BIO 240L.
BIO 240L  Genetics Laboratory  
Credits 1   Grading Basis Graded  
Students will explore both classic and molecular genetic techniques using genetic model organisms. Additionally, students will learn how to analyze large data sets using widely available data bases, data analysis programs and introductory coding.
Prerequisites: BIO 240 and minimum grade of "C-" in BIO 150 and BIO 150L. Corequisites: BIO 240.
BIO 245  General Microbiology  
Credits 3   Grading Basis Graded  
A study of the microorganisms, their significance, evolution, structure and function, genetics and the systems in which they exist.
Prerequisites: BIO 245L and BIO 103 or BIO 140 or CHEM 120 or CHEM 131 or ISCI 101 or equivalent. Corequisites: BIO 245L and BIO 103 or BIO 140 or CHEM 120 or CHEM 131 or ISCI 101 or equivalent.
BIO 245L  General Microbiology Laboratory  
Credits 1   Grading Basis Graded  
This laboratory course is designed to complement and supplement the BIO 245 lecture course.
Prerequisites: BIO 245 and BIO 103 or BIO 140/BIO 140L or CHEM 120 or CHEM 131 or ISCI 101 or equivalent. Corequisites: BIO 245 and BIO 103 or BIO 140/BIO 140L or CHEM 120 or CHEM 131 or ISCI 101 or equivalent.
BIO 246  Microbiology Seminar  
Credits 1   Grading Basis Graded  
Seminars, readings and discussions of the primary scientific literature with a focus on the current research in the field of microbiology.
Prerequisites: BIO 140, BIO 140L and declared microbiology concentration.
BIO 250  Quantitative Ecology and Evolution  
Credits 3   Grading Basis Graded  
Students will use an interactive e-text application to explore the changing natural world through modeling and simulation in a discovery-based classroom environment. Throughout every unit, the relationship among evolution, ecology and the environment are woven together using current research from primary literature. Evolution is explored in many relevant contexts, including artificial and natural selection of GMOs and of antibiotic resistance. In a module covering the evolution of decision making, students will learn quantitative approaches to game theory, optimal foraging and sexual selection. An understanding of population ecology and evolution is gained as students manipulate models to understand competition and predator-prey dynamics with real case studies of both microbes and endangered species. Climate change is discussed through the use of mathematical models and current and historical data.
Prerequisites: BIO 250L and a minimum grade of "C-" in BIO 150 and BIO 150L or GEOL 110, GEOG 210 or ISAT 112. Corequisites: BIO 250L.
BIO 250L  Quantitative Ecology and Evolution Laboratory  
Credits 1   Grading Basis Graded  
Hands-on laboratory and field-based experiences which emphasize experimental design and both statistical and quantitative analyses, with an emphasis on oral and written professional communication.
Prerequisites: BIO 250 and a minimum grade of "C-" in BIO 150 and BIO 150L or GEOL 110, GEOG 210 or ISAT 112. Corequisites: BIO 250.
BIO 260  Foundations of Human Anatomy and Physiology  
Credits 4   Grading Basis Graded  
An introduction to anatomy (structure) and physiology (function) of the human body and its organ systems which will provide a strong foundation in the relationship of human structure and function. BIO 260 is designed to meet the Virginia Science Content educational guidelines for A&P. Credit may not be earned in both BIO 260 and BIO 270/BIO 270L and BIO 290/BIO 290L.
Prerequisites: BIO 140 and BIO 140L; Students in the following majors and minors are not eligible for this course: Dietetics, Health Sciences, Kinesiology and Nursing and PPH. Credit may not be earned in both BIO 260 and BIO 270/270L and BIO 290/290L.
BIO 270  Human Physiology [C3NS]  
Credits 3   Grading Basis Graded  
An introduction to basic physiological principles using humans as the primary organism. Physiological adaptations will be examined at the molecular through organismal levels. Intended for students in health-related fields and The Natural World of the general education program. Not available for biology or biotechnology major credit. Credit for BIO 270/BIO 270L and BIO 290/BIO 290L may be transferred together to JMU only when transferable credits for two semesters of anatomy and physiology (I & II) are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO.
Prerequisites: BIO 270L; CHEM 120 or CHEM 131; and MATH 220 or MATH 229 or COB 191. Credit may not be earned in both BIO 270/BIO 270L and BIO 260. Corequisites: BIO 270L; CHEM 120 or CHEM 131; and MATH 220 or MATH 229 or COB 191.
BIO 270L  Human Physiology Laboratory [C3L]  
Credits 1   Grading Basis Graded  
This laboratory course is conducted to directly observe how the body's systems work and how scientific knowledge is accumulated in conjunction with the BIO 270 lecture course. Organizational and leadership skills are promoted by individual and group laboratory activities. Credit for BIO 270L and BIO 290L may be transferred together to JMU only when transferrable credits for two semesters of anatomy and physiology (I & II) lab are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO. May be used for general education credit.
Prerequisites: BIO 270, CHEM 120 or CHEM 131, and MATH 220 or MATH 229 or COB 191. Credit may not be earned in both BIO 270/BIO 270L and BIO 260. Corequisites: BIO 270, CHEM 120 or CHEM 131, and MATH 220 or MATH 229 or COB 191.
BIO 290  Human Anatomy  
Credits 3   Grading Basis Graded  
A regionally based study of the human body. Emphasis on major body structures and function is reinforced through hands-on examination of prosected cadaver specimens and other anatomical resources during the prerequisite or corequisite laboratory experience. Credit for BIO 270/BIO 270L and BIO 290/BIO 290L; may be transferred together to JMU only when transferrable credits for two semesters of Anatomy & Physiology (I & II) are completed at the same institution. A single semester, or courses from different institutions, transfer as BIO OOO.
Prerequisites: BIO 290L. Credit may not be earned in both BIO 290 and BIO 260.
BIO 290L  Human Anatomy Laboratory  
Credits 1   Grading Basis Graded  
A regionally-based study of the human body. Emphasis on major body structures and function through hands-on examination of prosected cadaver specimens and other anatomical resources. Credit for BIO 270L and BIO 290L may be transferred together to JMU only when transferrable credits for two semesters of anatomy and physiology (I & II) lab are completed at the same institution. A single semester transfer, or courses from different institutions, transfer as BIO OOO.
Prerequisites: BIO 290. Credit may not be earned in both BIO 290/BIO 290L and BIO 260. Corequisites: BIO 290.
BIO 301  Introductory Neuroscience  
Credits 3   Grading Basis Graded  
This course will examine molecular control of neuronal function. Topics include the structure and function of neuronal excitability, chemical and contact mediated neuronal communication, developing and regenerating nervous systems, sensation and perception, learning and memory formation, repair from neuronal damage, and the neuronal pathways of sensation and motor control. In the context of these subjects, we will review the neuronal alterations that cause some common brain diseases.
Prerequisites: BIO 140/BIO 140L and CHEM 132, or by permission of the instructor for PSYC majors.
BIO 302  Bioethics for Biologists  
Credits 3   Grading Basis Graded  
In this primarily discussion-based class, students will develop an understanding of the impact of biological and medical advances on society and why biologists and citizens must be aware of the accompanying bioethical issues. The development of the bioethics field will be explored, and biological, medical and technological advances will be described. Students will explore these topics with appropriate bioethics readings, short writing assignments synopsizing the readings, group discussions and in-class presentations selected by the students.
Prerequisites: BIO 140 or permission of the instructor.
BIO 304  Cell and Molecular Biology  
Credits 3   Grading Basis Graded  
Students will develop a deeper understanding of the molecular mechanisms employed by procaryotic and eucaryotic cells. Topics will include (1) macromolecular structure and function and how macromolecules coordinate to maintain life, (2) molecular mechanisms that regulate the synthesis and flow of genetic information and (3) molecular aspects of homeostasis, bioenergetics and cell signaling.
Prerequisites: Minimum grade of "C" in BIO 240/BIO 240L and CHEM 132/CHEM 132L.
BIO 310  Marine Biology  
Credits 3   Grading Basis Graded  
An exploration of the functional biology, ecology, and biodiversity of marine organisms. Students will be provided with a general understanding of how the ocean works and how marine organisms operate within their environment. The diversity of marine organisms in the open sea and benthos will be surveyed and a discussion of the numerous threats impacting various marine ecosystems will also be included.
Prerequisites: BIO 250/BIO 250L.
BIO 316  Animal Development  
Credits 3   Grading Basis Graded  
This course integrates cell and molecular biology and genetics to understand the processes and mechanisms underlying body plan formation and organ formation in vertebrate animals and insects. The course additionally covers the development of muscle, skeleton and nervous tissues, the postembryonic phenomena of growth, metamorphosis and regeneration, and the developmental basis of evolutionary changes in animal anatomy.
Prerequisites: BIO 240/BIO 240L.
BIO 318  Experimental Vertebrate Development  
Credits 2   Grading Basis Graded  
Students design and carry out independent research projects on different aspects of frog or chick development. Skills include manipulating live embryos, raising embryos and larvae from eggs, using wax histology to make microscope slides, immunohistochemistry, 3D reconstruction and morphometry-based analyses, and filming animal behavior. Projects are hypothesis-driven and investigate patterns, mechanisms and behaviors involved in the development of skeleton, lungs, tails, limbs and other organs.
Prerequisites: BIO 140/BIO 140L.
BIO 320  Comparative Anatomy of Vertebrates  
Credits 4   Grading Basis Graded  
This course explores the anatomical evolution of vertebrates, including the phylogenetic, developmental and functional significance of structures and systems across the vertebrate family tree. Students will gain key competencies in tree-thinking, specimen dissection, comparing and conveying anatomical form, and evaluating and synthesizing information to generate hypotheses and propose future directions in the field of comparative vertebrate anatomy.
Prerequisites: BIO 150/BIO 150L
BIO 324  Human Genetics  
Credits 3   Grading Basis Graded  
An intermediate genetics course with an emphasis on human biology. Topics include cytogenetics, pedigree analysis, quantitative traits, mutation, epigenetics, genomics and ethical issues raised by developing technologies.
Prerequisites: BIO 240/BIO 240L.
BIO 325  Medical Parasitology  
Credits 3   Grading Basis Graded  
This course covers the study and medical implications of parasites that infect humans. Class activities will emphasize parasite morphology, modes of transmission, mechanisms of host entry and infection, niche selection, life cycles, pathogenesis, diagnosis, and treatment and control.
Prerequisites: BIO 240/BIO 240L.
BIO 326  Intermediate Topics in Biology  
Credits 1-4   Grading Basis Graded  
This course covers specified areas of biology taught at the 300 level. May be repeated for credit when course content changes. See MyMadison for prerequisites for specific topics.
BIO 327  Biological Illustration  
Credits 3   Grading Basis Graded  
Students will consider how the skills of visual art are used in the dissemination of data. Students will learn how to sketch, paint and digitally illustrate microscopic specimens, live and dead plants and animals, bones, cellular processes and scientific methodology. Students will be instructed in different illustration techniques and be encouraged to find their preferred medium to produce a portfolio of images. The course content can be modified to reflect the interests/needs of the students. Students are responsible for obtaining all materials required for completing exercises and projects. Students may also obtain their own biological subjects.
Prerequisites: BIO 150/BIO 150L
BIO 330  Evolution  
Credits 3   Grading Basis Graded  
This course provides an introduction to evolutionary biology, including evidence for evolution, natural selection, genetic drift, sexual selection, phylogenetics, genome evolution, speciation, macroevolution, the history of life on Earth and the evolution of infectious disease.
Prerequisites: BIO 250/BIO 250L.
BIO 340  Morphology and Anatomy of Vascular Plants  
Credits 4   Grading Basis Graded  
A detailed study of the comparative morphology and anatomy of tracheophytes.
BIO 342  Mathematical Models in Biology  
Cross-listed with: MATH 342  
Credits 3   Grading Basis Graded  
Introduction to dynamical models (discrete and continuous time) applied to biology. Tools of mathematical analysis from linear and nonlinear dynamics will be taught, including stability analysis of equilibrium, as well as appropriate use of software packages. Emphasis will be on model development and interpretation in the context of applications, including effective written and oral presentation.
Prerequisites: MATH 232 or MATH 235 or equivalent.
BIO 346  Laboratory in Bacterial Pathogenomics  
Credits 2   Grading Basis Graded  
A course-based-research laboratory course. Students isolate pathogenic bacteria from environmental samples, identify and characterize them, and sequence their whole genomes. Students learn the basics of microbial genomics, including genome assembly, annotation and comparative genomics methods to study mobile genetic elements, virulence, antibiotic resistance, etc. They also learn how these methods are used in the epidemiological tracking of pathogens.
Prerequisites: Minimum grade of "C" in BIO 245/BIO 245L.
BIO 348  Medical Microbiology  
Credits 3   Grading Basis Graded  
Students will learn about microorganisms of medical importance, mainly bacteria and viruses. Key topics for each organism include general cell structure, unique structures/functions, epidemiology of the disease that the organism causes, mechanisms of pathogenesis, isolation and identification of the organism, and treatment options.
Prerequisites: Minimum grade of "C" in BIO 245/BIO 245L.
BIO 348L  Medical Microbiology Laboratory  
Credits 1   Grading Basis Graded  
This laboratory course consists of a series of case studies that require the students to identify the likely causative agent of the symptoms described in the case study.
Prerequisites: BIO 348. Corequisites: BIO 348.
BIO 350  Paleobiology  
Cross-listed with: GEOL 350  
Credits 4   Grading Basis Graded  
The evolution and ecological structure of the biosphere from the origin of life to the present, emphasizing the evolution and paleobiology of animal life as shown by the fossil record. Lectures discuss methods used to interpret the fossil record and cover topics such as phylogeny and systematics, functional morphology, biostratigraphy, paleoecology, evolution and extinction. Laboratories focus on the major groups of invertebrates that are common in the geologic record.
Prerequisites: GEOL 230, BIO 150/BIO 150L or permission of the instructor.
BIO 354  Global Climate Change and Life: Ecological and Biological Impacts of Climate Variability  
Credits 4   Grading Basis Graded  
Global climate change is important to the distribution, diversity, health and survival of organisms. The biota have changed through evolution in part as a response to selection pressures from these variations. Living things can also adjust to change through phenotypic flexibility. This course examines, in a seminar/discussion format, the potential ecological impacts of past and current patterns of climate alteration on organisms.
Prerequisite: "C-" or better in one of the following: BIO 140/BIO 140L, GEOL 110, GEOL 115, ISAT 112, GEOG 210 or CHEM 353.
BIO 357  Galápagos Islands: Biodiversity and Conservation  
Credits 3   Grading Basis Graded  
A detailed study of the biodiversity, conservation, biogeography and natural history of the Galápagos Islands.
Prerequisites: BIO 150/BIO 150L.
BIO 360  Plant Biology  
Credits 3   Grading Basis Graded  
This course is an introduction to the biology of plants including evolution, diversity, form and function, ecology, and biotechnology.
Prerequisites: BIO 250/BIO 250L with minimum grades of "C-"; Corequisites: BIO 360L.
BIO 360L  Plant Biology Laboratory  
Credits 1   Grading Basis Graded  
An exploration of plant structure, function, evolution and biological diversity.
Prerequisites: BIO 360. Corequisites: BIO 360.
BIO 361  Biochemistry I  
Cross-listed with: CHEM 361  
Credits 3   Grading Basis Graded  
An introduction to the molecules and chemical reactions of living systems. Structure and function of important classes of biomolecules are explored and the relationship of structure to function is stressed. Basic metabolic sequences are discussed.
Prerequisites: CHEM 241 and permission of the instructor.
BIO 364  Human Uses of Plants  
Credits 3   Grading Basis Graded  
A survey of past, present and future uses of plants with emphasis on economically important plant families. Issues of cultivated plant origins, biodiversity and germplasm preservation are considered.
BIO 364L  Laboratory in Human Uses of Plants  
Credits 1   Grading Basis Graded  
An investigative examination of plants and their constituents with an emphasis on their physiological ecology, adaptations and economic utilization by humans.
Prerequisites: BIO 364. Corequisites: BIO 364.
BIO 370  Human and Animal Physiology  
Credits 4   Grading Basis Graded  
Design and function of cellular and organ physiology will be explored in both humans and other animals. The course will begin by using an organ system approach to introduce basic physiological principles and develop understanding of physiological processes which requires the integration of multiple organ systems functioning. The course is intended for biology majors and minors. Class activities will emphasize problem-solving and collaborative and independent learning. The laboratories will utilize computer simulations and animal/human experiments to examine principles of both physiology and scientific investigation.
Prerequisites: CHEM 132 and BIO 240/BIO 240L (minimum grade of "C-" in both lab and lecture) or BIO 304. One semester each of calculus and statistics is recommended.
BIO 375  Sensation and Perception  
Cross-listed with: PSYC 375  
Credits 3   Grading Basis Graded  
This course explores the nature and development of human sensory capabilities and processing, and how these affect perception of the environment. A potential list of the variety of systems reviewed includes hearing, vision, smell, taste and touch/pain, as well as phenomena such as the perception of balance.
Prerequisites: Declared Neuroscience concentration; PSYC 101 or PSYC 160; and MATH 220, 229, 285 or 318.
BIO 380  Advanced Microbiology Laboratory Techniques  
Credits 1   Grading Basis Graded  
This course will focus primarily on advanced microbiology laboratory techniques. The techniques may include microcopy, staining, autoclave use and preparation of media, maintenance of stock cultures, and spectroscopy. This course will help prepare students for research and advanced microbiology laboratory courses.
Prerequisites: BIO 245 and BIO 245L.
BIO 385  Biopsychology  
Cross-listed with: PSYC 385  
Credits 3   Grading Basis Graded  
This course is a survey of the neurological and chemical mechanisms which control behavior. Students will examine the brain and how it processes sensation, perception, cognition, movement, motivation, learning, memory and other behavioral processes of interest to psychologists.
Prerequisites: Declared Neuroscience concentration; PSYC 101 or PSYC 160; and MATH 220, 229, 285 or 318.
BIO 386  Field Botany  
Credits 4   Grading Basis Graded  
An in-depth survey of vascular plants in the field with emphasis on identification, diversity of form and function, and ecology. Laboratory topics will include techniques for sampling plant communities, identifying local flora and preserving botanical materials.
BIO 387  Environmental Microbiology  
Credits 3   Grading Basis Graded  
An examination of microbial diversity in the environment and the functional role of microbes in ecosystems around the world.
Prerequisites: Minimum grade of "C-" in BIO 245/BIO 245L.
BIO 387L  Environmental Microbiology Laboratory  
Credits 1   Grading Basis Graded  
This course is a field-based investigative lab experience exploring the structure and function of microbial communities and applications of microbiology.
Prerequisites: BIO 387. Corequisites: BIO 387.
BIO 395  Comparative Animal Behavior  
Cross-listed with: PSYC 395  
Credits 3   Grading Basis Graded  
This course covers aspects of the development, function and evolution of the behavior of nonhuman animals. Topics covered include intraspecies communication, feeding, aggression, territoriality, reproductive behavior and social behavior.
Prerequisites: Psychology majors: A "C-" or better in PSYC 211 or PSYC 213. Biology and biotechnology majors: BIO 250/BIO 250L, and one of the following (with a "C-" or better): MATH 205, MATH 220, MATH 231, MATH 235, MATH 285, MATH 318.
BIO 400  Geology and Ecology of the Bahamas  
Cross-listed with: GEOL 400, BIO 500  
Credits 3   Grading Basis Graded  
This course explores the geology and ecology of the shallow-water marine environment by examining the preeminent modern example, the Bahamas platform. The Bahamas provide an excellent model for understanding modern and ancient carbonate and reef deposits and a variety of terrestrial/aquatic habitats. Biological processes are responsible for many of the geological features of the Bahamas, so the course considers the biology/ecology of marine organisms in addition to geological topics.
Prerequisites: GEOL 110L or GEOL 115L or GEOL 211 or a 200- level GEOL or BIO course; at least four hours of additional lab science, at least sophomore status, and permission of the instructor.
BIO 402  Forest Ecology  
Cross-listed with: BIO 502  
Credits 4   Grading Basis Graded  
A study of the function, structure and composition of forested ecosystems. The effect of physical geography on the distribution of forest communities will be explored. Issues of forest management and restoration will also be considered. Field laboratory topics will include dendrology and sampling techniques within different forest successional stages.
Prerequisites: BIO 250/BIO 250L.
BIO 404  Evolutionary Analysis  
Credits 3   Grading Basis Graded  
An examination of the place of theoretical thought in biology. The concepts of phylogenetic relationships and the mechanisms of organic change as expressed through the principles of organic evolution will be stressed.
Prerequisites: BIO 240/BIO 240L.
BIO 405  Vertebrate Paleontology  
Cross-listed with: GEOL 405  
Credits 3   Grading Basis Graded  
A study of the origin and evolution of the vertebrates. Emphasis will be on understanding how the processes of Earth evolution and biological evolution have interacted through time to produce a coherent picture of vertebrate history.
Prerequisites: GEOL 230 or BIO 150/BIO 150L or BIO 250/BIO 250L or permission of the instructor.
BIO 410  Advanced Human Anatomy  
Credits 3   Grading Basis Graded  
An advanced study of topics in human anatomy using dissection techniques.
Prerequisites: BIO 290/BIO 290L or BIO 320 and permission of the instructor.
BIO 412  Mammalogy  
Credits 4   Grading Basis Graded  
An introduction to the study of mammals, incorporating evolutionary history, general physiology, reproductive biology, systematics, ecology, wildlife management and behavior, followed by review of mammalian taxonomic orders. Lecture is reinforced with laboratory and field experience. Completion of BIO 320 recommended.
BIO 415  Neuroanatomy and Neurogenic Communication Disorders  
Cross-listed with: CSD 415  
Credits 3   Grading Basis Graded  
This course is an introduction to neuroanatomy with emphasis on neurogenic communication disorders.
Prerequisites: CSD 208 or permission of the instructor.
BIO 418  Conservation Biology  
Credits 3   Grading Basis Graded  
Conservation biology is the study and management of biodiversity with the aim of protecting species, their habitats and ecosystems from excessive rates of extinction. The course will focus on ecological theory, population dynamics, conservation and restoration strategies, and ethical questions for conservation. The course will also teach students to analyze open-ended questions via case studies.
Prerequisites: BIO 250/BIO 250L with minimum grade of "C-".
BIO 419  Animals and their Environments  
Credits 4   Grading Basis Graded  
This course provides an exploration of terrestrial and aquatic animal ecology with a focus on the ecology of vertebrates in a rapidly changing world. Students will investigate how animal ecology is shaped by the environment and how animals in turn shape their biotic and abiotic environments. Lectures will be composed of small group work to synthesize information from primary literature readings and other sources. Field laboratory topics will involve travel to various local ecosystems. Students will build skills with techniques used in ecological studies focused on various local taxa and ecological communities. Students will build transferable skills in experimental design, field techniques, problem solving, data management, manipulation, visualization and analysis via activities embedded in both lecture and laboratory throughout the course. Students will use these skills to collaboratively design, complete and present course-based field research projects.
Prerequisites: BIO 250/BIO 250L with minimum grade of "C-".
BIO 425  Immunology  
Credits 3   Grading Basis Graded  
This course studies the molecular and cellular basis of the immune system. Topics include the properties of antigens and immunoglobulins, the development and regulation of humoral and cell-mediated immunity, resistance and immunization to infectious diseases, allergies and autoimmune and immunodeficiency disorders.
Prerequisites: BIO 240/BIO 240L.
BIO 425L  Immunology Laboratory  
Credits 1   Grading Basis Graded  
This course will introduce students to the theory and application of many of the methods currently used in clinical and research immunology. Laboratory exercises will focus on methods for identifying, quantifying and assessing functional activities of immune cells and molecules. Students will gain experience using experimental animals and in animal cell culture techniques.
Prerequisites: BIO 425. Corequisites: BIO 425.
BIO 426  Topics in Biology  
Credits 1-4   Grading Basis Graded  
Specified areas of biology. May be repeated for credit when course content changes. See MyMadison for prerequisites for specific topics.
BIO 427  Topics in Biology with Laboratory  
Credits 1-4   Grading Basis Graded  
Laboratory studies in special areas of biology to accompany BIO 426 or stand alone. May be repeated for credit when course content changes. An accompanying 3-credit BIO 426 course may be a corequisite. See MyMadison for prerequisites for specific topics.
BIO 430  Ornithology: Research and Current Advances  
Credits 4   Grading Basis Graded  
Students will design and engage in course-based research projects using modern approaches to ornithology. Classes will investigate current primary literature on ornithological research, recent technological advances and conservation. Lectures and labs will explore the biodiversity of birds, identification by sight and sound, and the ecology, evolution, physiology and behavior of birds. Labs will involve fieldwork, data collection and workshops such as sound analysis and geographic tracking. BIO 430 will be taught concurrently with BIO 530.
Prerequisites: BIO 250/BIO 250L. Credit may not be earned in both BIO 430 and BIO 530.
BIO 432  Light Microscopy  
Cross-listed with: BIO 532  
Credits 4   Grading Basis Graded  
This course covers the principles behind light microscopy, from the properties of light to the latest technologies in microscopy. Students will get hands-on experience with the different kinds of microscopes, including the confocal microscope. The course also covers fluorescent probes, advanced fluorescence techniques, digital imaging, methods of quantification and figure preparation for publication, with an emphasis on biological applications.
Prerequisites: BIO 240/BIO 240L.
BIO 443  Understanding Techniques in Neuroscience  
Credits 3   Grading Basis Graded  
A writing-intensive introduction to basic neurobiological processes that draws from molecular biology, genetics, biochemistry, behavioral biology, electrophysiology, pharmacology, computer science and optics. Topics will include both classic and state-of-the-art techniques. Special emphasis will be placed on framing techniques as tools to answer basic scientific questions in neuroscience. BIO 443 is taught concurrently with BIO 543. Credit may not be earned in both BIO 443 and BIO 543.
Prerequisites: BIO 240/BIO 240L or BIO 250/BIO 250L. Credit may not be earned in both BIO 443 and BIO 543.
BIO 444  Virology  
Credits 3   Grading Basis Graded  
A study of the fundamental aspects of both basic and medical virology. Credit may not be earned in both BIO 444 and BIO 544.
Prerequisites: Minimum grade of "C" in each of the following: CHEM 241, BIO 304 and BIO 240/BIO 240L.
BIO 445  Neurobiology  
Credits 4   Grading Basis Graded  
Molecular, cellular and network mechanisms underlying behavior will be studied using problem-solving, discussion, lecture and critical reading of the primary literature. Similarities and differences between nervous systems and computers will be explored. Laboratories will utilize contemporary electrophysiology and computer simulation to examine the neurobiology of simple animal model systems.
Prerequisites: BIO 140/BIO 140L or BIO 304.
BIO 446  Experimental Neurobiology  
Cross-listed with: BIO 546  
Credits 4   Grading Basis Graded  
The experimental basis of neurobiology will be explored in invertebrates and humans using modern neurobiological techniques, such as extracellular, intracellular, electromyogram and voltage clamp recording. The course will revolve primarily around the laboratory activities, with the single lecture section designed to support the laboratory. Students will be expected to complete a project that involves developing a new experimental approach or model system.
Prerequisites: BIO 140/BIO 140L or BIO 304.
BIO 447  Evolution and Ecology of Infectious Disease  
Cross-listed with: BIO 547  
Credits 3   Grading Basis Graded  
An introduction to the evolution and ecology of pathogenic microorganisms, with an emphasis on the bacteria. Emphasis will be placed on the study, discussion and critique of scientific literature, as well as formal presentation of scientific information and data.
Prerequisites: BIO 245/BIO 245L and BIO 250/BIO 250L.
BIO 448  Developmental Neurobiology  
Credits 3   Grading Basis Graded  
Exploration of molecular and cellular mechanisms that determine neuronal identity, migration, synaptogenesis, synaptic plasticity and neural systems organization. Critical and intensive evaluation and communication of primary literature.
BIO 449  Insect Ecology  
Cross-listed with: BIO 549  
Credits 4   Grading Basis Graded  
An overview of insect ecology from an evolutionary perspective, focusing on the processes that affect the diversity, distribution and abundance of insects in natural and managed ecosystems. The role of insects as model systems in understanding ecological and evolutionary principles is included, and current literature in the field is highlighted. Field surveys and experiments are emphasized, including general insect collection and identification.
Prerequisites: BIO 250/BIO 250L.
BIO 451  Current Topics in Human Development and Evolution  
Cross-listed with: BIO 551  
Credits 3   Grading Basis Graded  
Discussion-based course on the developmental changes involved in our evolution from ape-like ancestors; using the science of cloning and embryonic stem cells to prolong human life; the evolutionary theory of aging; the genetic conflict theory of human pregnancy; the developmental basis of variation in human sexuality; and the direct effects of environment on modern human development and evolution.
Prerequisites: BIO 240/BIO 240L.
BIO 452  Population Ecology  
Cross-listed with: BIO 552  
Credits 4   Grading Basis Graded  
Theoretical and applied aspects of distribution and abundance, population regulation, interactions between populations and conservation will be studied in selected organisms, including humans. Credit may not be earned in both BIO 452 and BIO 552.
Prerequisites: BIO 250/BIO 250L.
BIO 453  Microbial Ecology and Evolution  
Cross-listed with: BIO 553  
Credits 3   Grading Basis Graded  
The ecology of microorganisms will be covered, including those important in human health and in natural environments. Emphasis will be placed on the study and critique of scientific literature. Credit may not be earned in both BIO 453 and 553.
Prerequisites: BIO 245/BIO 245L and BIO 250/BIO 250L.
BIO 454  Introduction to Biometrics  
Cross-listed with: MATH 354  
Credits 4   Grading Basis Graded  
This course discusses the role of statistics in biological research and interpretation of biological phenomena. The course will cover topics of sampling, correlation, regression analysis, tests of hypotheses, commonly observed distributions in natural populations, nonparametric tests, goodness-of-fit tests and ANOVA. In order to fully comprehend the statistical analysis of those publications, students will review approximately half a dozen publications from different fields of biology.
Prerequisites: MATH 220, MATH 229, MATH 318 or equivalent.
BIO 455  Plant Physiology  
Cross-listed with: BIO 555  
Credits 4   Grading Basis Graded  
An in-depth study of plant function including metabolism, water relations, transport phenomena, growth and development, physiological ecology, and responses to pathogens and abiotic stress. Credit may not be earned in both BIO 455 and BIO 555.
Prerequisites: BIO 240/BIO 240L and CHEM 132.
BIO 456  Ecological Models and Data  
Credits 4   Grading Basis Graded  
Emerging issues in health and environmental sciences require an understanding of how to make inferences and decisions in the face of limited data and uncertainty. In the past few decades, advances in computational sciences have opened new ways of using and interpreting data. These advances are fundamentally changing how biologists approach statistics. This course introduces students to the principles of probability and likelihood that underpin these growing areas of statistics, and teaches students how to apply these principles to statistical computing. Examples come from ecological models and data and reflect general principles of working with discrete and continuous data, maximum likelihood and Bayesian estimation techniques, and using fundamental principles of probability to build and interpret mixed and mixture models. Work will be done using the open-source statistics program, R, and exercises will emphasize building skills by working with peers and by trial-and-error, both of which are key features of the open-source computing community.
Prerequisites: MATH 220 or MATH 229 or MATH 318; BIO 250; or permission of the instructor. Corequisites: BIO 250.
BIO 457  Biological Applications of Geographic Information Systems  
Credits 4   Grading Basis Graded  
This course will explore the various ways that geographic information systems (GIS) can be used to answer biological questions. Students will use GIS software to study applications in ecology, conservation biology, and environmental biology. No prior GIS experience required.
BIO 459  Freshwater Ecology  
Credits 4   Grading Basis Graded  
Functional relationships and productivity of freshwater communities are examined as they are affected by their physical, chemical and biotic environment. Organisms inhabiting lakes, ponds, rivers, streams and estuaries are studied at the population, community and ecosystem levels.
Prerequisites: BIO 250/BIO 250L and CHEM 132.
BIO 460  Plant Biotechnology  
Cross-listed with: BIO 560  
Credits 4   Grading Basis Graded  
Theory and practice of growing isolated plant cells, tissues and organs.
Prerequisites: BIO 150/BIO 150L and CHEM 132.
BIO 467  Human Cardiovascular Physiology  
Credits 3   Grading Basis Graded  
An in-depth look at the human cardiovascular system by means of advanced physiology with clinical applications and case-based learning. While the course is focused on the human heart and blood vessels, other body systems will be discussed in the context of their association and integration with the cardiovascular system.
Prerequisites: BIO 370 or minimum grade of "B-" in BIO 270/BIO 270L.
BIO 468  Endocrinology  
Cross-listed with: BIO 568  
Credits 3   Grading Basis Graded  
Study of endocrine organs and mechanisms of action of hormones. Students will be involved in interactive lectures and team-based learning activities to understand endocrine functions and disorders.
BIO 472  Human Metabolism  
Credits 3   Grading Basis Graded  
This course will focus on the cellular physiological mechanisms responsible for regulation of normal human metabolism and place them in the context of the development of chronic disease processes.
Prerequisites: CHEM 241 and BIO 240/BIO 240L or permission of the instructor.
BIO 474  Reproductive Physiology  
Credits 3   Grading Basis Graded  
This is an advanced-level vertebrate physiology course in which students will learn reproductive anatomy, physiology, development and behavior of a variety of organisms with humans serving as the foundational species. Innate and manipulated physiological mechanisms controlling reproduction will be examined at the molecular through organismal levels. Intended for students in organismal biology and health-related fields.
Prerequisites: BIO 370 or both BIO 270 and BIO 290.
BIO 477  The Genetics of Cancer  
Cross-listed with: BIO 577  
Credits 3   Grading Basis Graded  
Exploration of the genetic and epigenetic factors that drive the evolution of cancer cells, taking into account both inherited and environmental contributions to this process. The cellular mechanisms debilitated or subverted during cancer development will be studied, and student teams will demonstrate their understanding of the material through the diagnosis, genetic characterization and treatment of a hypothetical cancer patient.
Prerequisites: BIO 240/BIO 240L.
BIO 478  Aging and Neurodegeneration  
Credits 3   Grading Basis Graded  
This course will examine cellular mechanisms, genetics and environmental factors that underlie the onset and progression of age-related neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's and Amyotrophic lateral sclerosis (ALS). This course will build on students' foundational knowledge of cell function, apoptosis and genetics to understand mechanisms that initiate and drive the proliferation neuronal cell death in age-related neurodegenerative diseases. In this course, students also study advancements in research and technology that have led to improved diagnosis and treatment of neurodegenerative disease.
BIO 480  Advanced Molecular Biology  
Credits 3   Grading Basis Graded  
This course is a study of the history, basic principles and ethical considerations in the field of molecular biology. Students will learn about the structure and function of nucleic acids, proteins and other cellular macromolecules to appreciate the power and limitations of current resources and knowledge.
Prerequisites: CHEM 241 and a "C-" or better in BIO 240/BIO 240L.
BIO 480L  Advanced Molecular Biology Lab  
Credits 1   Grading Basis Graded  
This course is a study of the applied practices in the field of molecular biology. Students will participate in hands-on wet bench and computational experiments analyzing nucleic acids, proteins and other cellular macromolecules to appreciate the power and limitations of current resources and knowledge.
Prerequisites: BIO 480 and CHEM 241 and a "C-" or better in BIO 240/BIO 240L. Corequisites: BIO 480.
BIO 481  Genomics  
Cross-listed with: BIO 581  
Credits 4   Grading Basis Graded  
This advanced biology course is designed for students to learn about the structure and function of genomes, to develop facility in web-based tools and resources, and to appreciate the power and limitations of current resources and knowledge. Focus is on the biological questions that genomics can help to answer. Laboratory exercises will be sequencing and analyzing genomic DNA.
Prerequisites: BIO 240/BIO 240L.
BIO 482  Human Histology  
Credits 4   Grading Basis Graded  
Students will examine microscopic structure of cells, tissues and major organ systems of the body. Basic anatomical and physiological function is presented to emphasize the histological significance of the examined organ systems.
Prerequisites: BIO 260, BIO 270/BIO 270L, BIO 290/BIO 290L, or BIO 370. Credit may not be earned in both BIO 482 and BIO 582.
BIO 483  Bioinformatics  
Cross-listed with: BIO 583  
Credits 4   Grading Basis Graded  
Focuses on building databases and computer programs to manage and analyze biological sequence data, and secondarily on theoretical aspects. The overall objective is to learn current information about the intersection of information science and biology, to develop facility in the many web-based tools and resources for further studies and research in genomics/bioinformatics, and to appreciate the power and limitations of current resources and knowledge.
Prerequisites: BIO 240/BIO 240L.
BIO 484  Aquatic Microbiology  
Credits 3   Grading Basis Graded  
This research-embedded course will introduce students to the techniques and experimental design currently used in aquatic microbial ecology through both literature and laboratory procedures. Students will participate in projects that are currently a component of the instructor's research program. BIO 484 will be taught concurrently with BIO 584.
Prerequisites: BIO 245/BIO 245L or equivalent. Students may not earn credit in both BIO 484 and BIO 584.
BIO 486  Systematics of Vascular Plants  
Credits 4   Grading Basis Graded  
Study of systematic theory and an overview of the classification and evolution of higher plants, with particular attention to flowering plant families. Techniques for plant identification and collection and for construction of phylogenies will be taught in lab.
BIO 489  Topics in Science Pedagogical Content Knowledge  
Cross-listed with: MSSE 495  
Credits 2   Grading Basis Graded  
Contributes to the further development of pre-service secondary science teachers' pedagogical content knowledge. Students will engage in education research to gain experience and develop instructional practices relevant to the Virginia Standards of Learning. To supplement their understanding of scientific concepts and the process of science, the focus will be on the nature of science encompassing literature from the history, philosophy, and sociology of science.
Prerequisites: BIO 150/BIO 150L.
BIO 490  Mechanics of Animal Movement  
Credits 4   Grading Basis Graded  
The interactions of organisms with their physical environment. Concepts from fluid and solid mechanics are applied to biological form and function.
Prerequisites: BIO 150/BIO 150L.
BIO 491  Scientific Writing, Presentation and Critical Thinking  
Credits 2   Grading Basis Credit / No Credit  
A discussion-based course for the development of the fundamental thinking, writing and presentation skills necessary to be a successful researcher. This course is required for all Biology Track I and II Honors students in their sophomore year, and is strongly recommended for all Biology majors who are intending to do research. Offered as credit/no credit only.
Prerequisites: BIO 140/BIO 140L.
BIO 492  Mentored Biology Course Assistant  
Credits 0-1   Grading Basis Credit / No Credit  
Students are trained in the support and function of undergraduate biology courses. Students must contact and make arrangements with the supervising instructor in the term prior to registration. May be repeated when course content and/or student responsibilities within the course change. Offered as credit/no credit only.
Prerequisites: GPA of 2.5 or higher and permission of the instructor.
BIO 493  Pre-Veterinary Student Internship  
Credits 2   Grading Basis Credit / No Credit  
Students are supervised by veterinarians and lab technicians in diagnostic lab activities at a regional animal health laboratory. A proposal and final presentation are required. Enrollment is limited to 1-2 individuals per term and students are advised to contact the Pre-Veterinary coordinator to be waitlisted. Offered as credit/no credit only.
Prerequisites: Completion of BIO 240/BIO 240L, GPA of 2.5 or higher and permission of the instructor.
BIO 494  Internship in Biology  
Credits 1-2   Grading Basis Credit / No Credit  
Students participate in research or applied biology outside of this university. Students must contact and obtain approval of a supervising instructor at the off campus location and with the department internship coordinator in the term prior to registration. A proposal must be approved prior to registration and a final paper or presentation will be completed. Offered as credit/no credit only.
Prerequisites: Biology or biotechnology major with a minimum of eight biology credit hours and a GPA of 2.5 or greater.
BIO 496  Biological Research  
Credits 0-1   Grading Basis Credit / No Credit  
Students pursue a lab or field research project in a selected area of biology with a faculty research mentor. This could be research techniques (lab or field), literature review or both. Students must contact and make arrangements with a supervising instructor in the term prior to registration. This course may be repeated, and up to 2 credits may be used to partially satisfy one upper level laboratory requirement for the biology major. This course is offered as credit/no-credit only.
Prerequisites: GPA of 2.5 or greater.
BIO 497  Advanced Biological Research  
Credits 0-1   Grading Basis Credit / No Credit  
Students pursue a lab or field research project in a selected area of biology with a faculty research mentor. Students must contact and make arrangements with a supervising instructor in the term prior to registration. Students must complete a proposal or form of scientific communication by the end of the semester, such as a conference presentation, Biosymposium presentation, lab presentation or research paper, at the discretion of the instructor. This course may be repeated, and may be used towards the combined 3 credits of research to satisfy one upper level lab requirement for the biology major. This course is offered as credit/no credit only.
Prerequisites: GPA of 2.5 or higher and permission of the instructor.
BIO 499A  Senior Project  
Credits 2   Grading Basis Graded  
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
BIO 499B  Senior Project  
Credits 2   Grading Basis Graded  
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
BIO 499C  Senior Project  
Credits 2   Grading Basis Graded  
Three semester courses taken as Parts A, B and C; 2 credits each. Expectations, requirements and prerequisites are defined in the department senior project policy. Students must contact and make arrangements with a supervising instructor in the term prior to registration.
BIO 500  Geology and Ecology of the Bahamas  
Cross-listed with: GEOL 400, BIO 400  
Credits 3   Grading Basis Graded  
This course explores the geology and ecology of the shallow-water marine environment by examining the preeminent modern example, the Bahamas platform. The Bahamas provide an excellent model for understanding modern and ancient carbonate and reef deposits and a variety of terrestrial/aquatic habitats. Biological processes are responsible for many of the geological features of the Bahamas, so the course considers the biology/ecology of marine organisms in addition to geological topics.
BIO 501  Workshops in Biology  
Credits 1-3   Grading Basis Graded  
Concentrated study in particular areas of biology. No credit is allowed toward the Master of Science degree requirements and no more than one workshop may be applied toward a minor in biology.
BIO 502  Forest Ecology  
Cross-listed with: BIO 402  
Credits 4   Grading Basis Graded  
A study of the function, structure and composition of forested ecosystems. The effect of physical geography on the distribution of forest communities will be explored. Issues of forest management and restoration will also be considered. Field laboratory topics will include dendrology and sampling techniques within different forest successional stages.
BIO 504  Evolution  
Credits 3   Grading Basis Graded  
Population change as brought about by mechanisms of organic evolution. Molecular biology is integrated with evolutionary biology and concepts of phylogenetic relationships resulting from the process of speciation are stressed. A seminar/research project is required.
Prerequisites: Credit may not be earned in both BIO 404 and BIO 504.
BIO 512  Graduate Mammalogy  
Credits 4   Grading Basis Graded  
This course provides an introduction to the study of mammals, incorporating current literature and methods of data analysis in the study of mammals. Topics covered include evolutionary history, general physiology, reproductive biology, systematics, ecology, wildlife management and behavior, followed by review of mammalian taxonomic orders. Lectures are reinforced with specimen-based, team-led laboratory and field experiences, with an over-arching camera study of native species. Students should have a background in introductory ecology and comparative anatomy of vertebrates or human anatomy.
BIO 513  Human Gross Anatomy with Clinical Applications  
Credits 9   Grading Basis Graded  
An advanced study of human anatomy with cadaver dissection. Emphasis is given to a clinical perspective and the evolution and development of human structure within a comparative context.
Prerequisites: A rigorous undergraduate course in anatomy, admission to the Physician Assistant program or permission of the instructor.
BIO 514  Clinical Anatomy for Occupational Therapists  
Credits 4   Grading Basis Graded  
This course offers an in-depth study of the structure of the musculoskeletal and peripheral nervous system of the human body. Specific structural and neural pathologies will be examined in regards to impact on occupational performance. Laboratory experiences involving cadaver dissection, skeletal material, models and audiovisual technology will be utilized.
Prerequisites: Admission to the occupational therapy program.
BIO 516  Physiology and Pathophysiology  
Credits 6   Grading Basis Graded  
An advanced clinically-oriented study of normal human physiology, as well as an introduction to the basics of human disease processes (pathophysiology). The course serves as a foundation for future courses in clinical medicine, pharmacology and diagnostic methods.
Prerequisites: Admission to the physician assistant studies program.
BIO 517  Pathophysiology for Physician Assistants II  
Credits 6   Grading Basis Graded  
An advanced clinically-oriented study of human physiology and the alterations in body functions that underlie diseases in humans. It serves as a foundation for courses in the clinical medicine.
Prerequisites: Admission to the physician assistant program and successful completion of all previous courses in the curriculum, or permission of the program director.
BIO 518  Graduate Conservation Biology  
Credits 3   Grading Basis Graded  
Conservation biology is the study and management of biodiversity with the aim of protecting species, their habitats and ecosystems from excessive rates of extinction. The course will focus on ecological theory, population dynamics, conservation and restoration strategies, and ethical questions for conservation. The course will guide students in analyzing open-ended questions via case studies, in-depth discussions and writing assignments. Graduate students will develop and implement a teaching module, develop refined communication and leadership skills, and write a comprehensive conservation action plan. Students should have previous coursework in ecology and evolution or equivalent.
Prerequisites: Credit may not be earned in both BIO 418 and BIO 518.
BIO 526  Graduate Topics in Biology  
Credits 3-4   Grading Basis Graded  
Studies in special areas of biology. May be repeated with change in topic or change in subject matter within a topic.
BIO 527  Graduate Laboratory/Field Topics in Biology  
Credits 1-4   Grading Basis Graded  
Advanced Laboratory studies in graduate level Biology topics. May be repeated for course credit when course content changes.
BIO 530  Ornithology: Research and Current Advances  
Credits 4   Grading Basis Graded  
Students will design and engage in course-based research projects using modern approaches to ornithology. Classes will investigate current primary literature on ornithological research, recent technological advances and conservation. Lectures and labs will explore the biodiversity of birds, identification by sight and sound, and the ecology, evolution, physiology and behavior of birds. Labs will involve fieldwork, data collection and workshops such as sound analysis and geographic tracking. BIO 530 will be taught concurrently with BIO 430.
Prerequisites: Credit may not be earned in both BIO 430 and BIO 530.
BIO 532  Light Microscopy  
Cross-listed with: BIO 432  
Credits 4   Grading Basis Graded  
This course covers the principles behind light microscopy, from the properties of light to the latest technologies in microscopy. Students will get hands-on experience with the different kinds of microscopes, including the confocal microscope. The course also covers fluorescent probes, advanced fluorescence techniques, digital imaging, methods of quantification and figure preparation for publication, with an emphasis on biological applications.
BIO 540  Functional Neuroscience for Occupational Therapists  
Credits 3   Grading Basis Graded  
This course examines the structure and function of the human nervous system with applications to occupational engagement across the lifespan. The occupational therapy process is applied to explore the influences of common neurological conditions on occupational performance, performance skills, client factors and performance patterns of clients within environmental and personal contexts and the occupational therapy role.
Prerequisites: Admission to the occupational therapy program.
BIO 543  Understanding Techniques in Neuroscience  
Credits 3   Grading Basis Graded  
A writing-intensive introduction to basic neurobiological processes that draws from molecular biology, genetics, biochemistry, behavioral biology, electrophysiology, pharmacology, computer science and optics. Topics will include both classic and state-of-the-art techniques. Special emphasis will be placed on framing techniques as tools to answer basic scientific questions in neuroscience. BIO 543 is taught concurrently with BIO 443. Credit may not be earned in both BIO 443 and BIO 543.
Prerequisites: Credit may not be earned in both BIO 443 and BIO 543.
BIO 544  Virology  
Credits 3   Grading Basis Graded  
A lecture seminar course considering the fundamental principles of basic and medical virology and an analysis of the structure, chemistry and replication of representative RNA and DNA animal viruses at the molecular level.
Prerequisites: Credit may not be earned in both BIO 444 and BIO 544.
BIO 546  Experimental Neurobiology  
Cross-listed with: BIO 446  
Credits 4   Grading Basis Graded  
The experimental basis of neurobiology will be explored in invertebrates and humans using modern neurobiological techniques, such as extracellular, intracellular, electromyogram and voltage clamp recording. The course will revolve primarily around the laboratory activities, with the single lecture section designed to support the laboratory. Students will be expected to complete a project that involves developing a new experimental approach or model system.
BIO 547  Evolution and Ecology of Infectious Disease  
Cross-listed with: BIO 447  
Credits 3   Grading Basis Graded  
An introduction to the evolution and ecology of pathogenic microorganisms, with an emphasis on the bacteria. Emphasis will be placed on the study, discussion and critique of scientific literature, as well as formal presentation of scientific information and data.
BIO 548  Developmental Neurobiology  
Credits 3   Grading Basis Graded  
Advanced exploration of molecular and cellular mechanisms that determine neuronal identity, migration, synaptogenesis, synaptic plasticity and neural systems organization. Critical and intensive evaluation and communication of advanced primary literature. Graduate students will lead discussions on scientific literature that will be held to a higher standard of scientific rigor, demonstrating graduate-level mastery of the topics.
Prerequisites: Credit may not be earned in both BIO 448 and BIO 548.
BIO 548L  Developmental Neurobiology Laboratory  
Credits 1   Grading Basis Graded  
Advanced laboratory projects exploring molecular and cellular mechanisms of neural development, including neuronal identity, migration, synaptogenesis, synaptic plasticity or neural systems organization. Introduction to current and advanced research techniques in developmental neurobiology. Independent design and execution of research projects under instructor guidance. Graduate students will lead experimental projects that will be held to a higher standard of scientific rigor, demonstrating graduate-level mastery of the topics.
BIO 549  Insect Ecology  
Cross-listed with: BIO 449  
Credits 4   Grading Basis Graded  
An overview of insect ecology from an evolutionary perspective, focusing on the processes that affect the diversity, distribution and abundance of insects in natural and managed ecosystems. The role of insects as model systems in understanding ecological and evolutionary principles is included, and current literature in the field is highlighted. Field surveys and experiments are emphasized, including general insect collection and identification.
BIO 550  Neurobiology  
Credits 4   Grading Basis Graded  
Molecular, cellular and network mechanisms underlying behavior will be studied using problem-solving, discussion, lecture and reading of primary literature. Similarities and differences between nervous systems and computers will be explored. Laboratories will utilize contemporary electrophysiology and computer simulation to examine the neuobiology of simple animal model systems.
BIO 551  Current Topics in Human Development and Evolution  
Cross-listed with: BIO 451  
Credits 3   Grading Basis Graded  
Discussion-based course on the developmental changes involved in our evolution from ape-like ancestors; using the science of cloning and embryonic stem cells to prolong human life; the evolutionary theory of aging; the genetic conflict theory of human pregnancy; the developmental basis of variation in human sexuality; and the direct effects of environment on modern human development and evolution.
BIO 552  Population Ecology  
Cross-listed with: BIO 452  
Credits 4   Grading Basis Graded  
Theoretical and applied aspects of distribution and abundance, population regulation, interactions between populations and conservation will be studied in selected organisms, including humans. Credit may not be earned in both BIO 452 and BIO 552.
BIO 553  Microbial Ecology and Evolution  
Cross-listed with: BIO 453  
Credits 3   Grading Basis Graded  
The ecology of microorganisms will be covered, including those important in human health and in natural environments. Emphasis will be placed on the study and critique of scientific literature. Credit may not be earned in both BIO 453 and 553.
BIO 554  Biometrics  
Credits 4   Grading Basis Graded  
The design of biological experiments and applications of statistical techniques in ecology, cell biology, physiology, behavior, systematics, genetics and evolution. Experiments and data from the biological literatures will be emphasized. Statistical software packages will be used. A seminar/research project involving advanced applications is required.
BIO 555  Plant Physiology  
Cross-listed with: BIO 455  
Credits 4   Grading Basis Graded  
An in-depth study of plant function including metabolism, water relations, transport phenomena, growth and development, physiological ecology, and responses to pathogens and abiotic stress. Credit may not be earned in both BIO 455 and BIO 555.
BIO 556  Graduate Ecological Models and Data  
Credits 4   Grading Basis Graded  
Recent advances in computational sciences have facilitated methods of making inferences from data, fundamentally changing how biologists approach statistics. Students will learn how methods were developed and apply them to ecological examples. Topics include general principles of working with discrete and continuous data, maximum likelihood and Bayesian estimation techniques, and implementation of mixed and mixture models.  Students address ecological questions using data from a variety of currently available resources, and generate professional level reports and manuscripts. Introductory coursework in statistics is expected.
Prerequisites: Credit may not be earned in both BIO 456 and BIO 556.
BIO 557  Biological Applications of Geographic Information Systems  
Credits 4   Grading Basis Graded  
This course will explore the various ways that geographic information systems (GIS) can be used to answer biological questions. Students will use GIS software to study applications in ecology, conservation biology and environmental biology. A seminar/research project involving advanced applications is required. No prior GIS experience is required.
BIO 559  Aquatic Ecology  
Credits 4   Grading Basis Graded  
Functional relationships and productivity of freshwater communities are examined as they are affected by their physical, chemical and biotic environment. Organisms inhabiting lakes, ponds, rivers, streams and estuaries are studied at the population, community and ecosystem levels. Preparation of seminar topic papers required. Credit may not be earned in both BIO 459 and BIO 559.
BIO 560  Plant Biotechnology  
Cross-listed with: BIO 460  
Credits 4   Grading Basis Graded  
Theory and practice of growing isolated plant cells, tissues and organs.
BIO 567  Data Management Skills  
Cross-listed with: GRAD 550  
Credits 1   Grading Basis Satisfactory/Unsatisfactory  
This eight-week course is intended to serve as an engaging introduction to develop data management skills and provide an exploration into several aspects of managing data from idea conception to post-project completion.
BIO 568  Endocrinology  
Cross-listed with: BIO 468  
Credits 3   Grading Basis Graded  
Study of endocrine organs and mechanisms of action of hormones. Students will be involved in interactive lectures and team-based learning activities to understand endocrine functions and disorders.
BIO 574  Graduate Reproductive Physiology  
Credits 3   Grading Basis Graded  
In this graduate level vertebrate physiology course, students will learn reproductive anatomy, physiology, development and behavior of a variety of organisms with humans serving as the foundational species. Innate and manipulated physiological mechanisms controlling reproduction will be examined at the molecular through organismal levels with an emphasis on understanding experimental approaches to physiology and reading a variety of scientific literature, from clinical studies to field biology. Students will curate scientific literature readings, teach undergraduates to understand the peer-reviewed literature and develop advanced-level assessments. Students should have previous coursework in physiology.
Prerequisites: Credit may not be earned in both BIO 474 and BIO 574.
BIO 580  Advanced Molecular Biology  
Credits 4   Grading Basis Graded  
Cellular constituents and genetics are emphasized at the molecular level. Credit may not be earned in both BIO 480 and BIO 580.
BIO 581  Genomics  
Cross-listed with: BIO 481  
Credits 4   Grading Basis Graded  
This advanced biology course is designed for students to learn about the structure and function of genomes, to develop facility in web-based tools and resources, and to appreciate the power and limitations of current resources and knowledge. Focus is on the biological questions that genomics can help to answer. Laboratory exercises will be sequencing and analyzing genomic DNA.
BIO 582  Human Histology  
Credits 4   Grading Basis Graded  
This course presents the microscopic structure of cells, tissues and organs to explain normal physiological function and provides a basis for understanding disease mechanisms and altered cellular states. A special research project is required. Credit may not be earned in both BIO 482 and BIO 582.
BIO 583  Bioinformatics  
Cross-listed with: BIO 483  
Credits 4   Grading Basis Graded  
Focuses on building databases and computer programs to manage and analyze biological sequence data, and secondarily on theoretical aspects. The overall objective is to learn current information about the intersection of information science and biology, to develop facility in the many web-based tools and resources for further studies and research in genomics/bioinformatics, and to appreciate the power and limitations of current resources and knowledge.
BIO 584  Aquatic Microbiology  
Credits 3   Grading Basis Graded  
This research-embedded course will introduce students to the techniques and experimental design currently used in aquatic microbial ecology through both literature and laboratory procedures. Students will participate in projects that are currently a component of the instructor's research program. BIO 584 will be taught concurrently with BIO 484. Students may not earn credit in both BIO 484 and BIO 584.
Prerequisites: Credit may not be earned in both BIO 484 and BIO 584.
BIO 586  Systematics of Vascular Plants  
Credits 4   Grading Basis Graded  
Study of systematic theory and an overview of the classification and evolution of higher plants, with particular attention to flowering plant families. Techniques for plant identification and collection and for construction of phylogenies will be taught in lab. An independent project and presentation will be required. Prerequisites: general botany and cell biology or equivalents. Credit may not be earned in both BIO 486 and BIO 586.
BIO 590  Mechanics of Animal Movement  
Credits 4   Grading Basis Graded  
The interactions of organisms with their physical environment. Concepts from fluid and solid mechanics are applied to biological form and function.
BIO 600  College Science Teaching  
Credits 2   Grading Basis Graded  
Students will explore effective teaching strategies in the sciences. Emphasis will be placed on how to prepare and teach laboratory and lecture courses, including effective instructional technologies and exam preparation. Discussions of teaching experiences and mentor and peer evaluations of the students' teaching skills will be included.
Corequisites: BIO 601.
BIO 601  Mentored Teaching  
Credits 1   Grading Basis Graded  
Students continue their exploration of effective teaching strategies in the biological sciences as they enter into their first teaching assignment in the department. Students will work under a faculty teaching mentor who will guide the students through their first teaching experience in the Department of Biology. Emphasis will be placed on mentor and peer evaluations of the students' teaching skills. May be repeated for up to two credits for different teaching assignments.
Corequisites: BIO 600.
BIO 602  Effective Scientific Communication  
Credits 2   Grading Basis Graded  
Students will develop skills in effective oral and written communications in the biological sciences. Emphasis will be placed on student learning styles, how to prepare an effective lecture or research seminar, effective use of presentation technologies and effective scientific writing.
BIO 603  Scientific Presentations  
Credits 1   Grading Basis Satisfactory/Unsatisfactory  
A forum for students to present their research and/or teaching materials to their peers and receive constructive feedback on their progress. Presentations may take the form of informal "chalk talks," journal club presentations and/or formal presentations. This course is graded on a satisfactory/unsatisfactory (S/U) basis. May be repeated for up to two credits.
BIO 611  Data Analysis and Visualization in Biology  
Credits 2-3   Grading Basis Graded  
This class will cover multiple aspects of data, including collection and curation, analysis, and visualization. For analysis and visualization, students will use the statistical programming language R. By the end of this course students will be comfortable using R to manage, manipulate, visualize and analyze their own data, including the ability to make publication-ready figures. Emphasis will be placed on the application of statistical visualization approaches to biologically relevant data using current standards in the field of biology.
BIO 620  Methods and Management of Research  
Credits 1-3   Grading Basis Satisfactory/Unsatisfactory  
The purpose of this course is to provide individualized training and mentoring in designing, development and completion of a master's level thesis project. Students will develop a research question in collaboration with their research mentor, compose and manage a thesis committee including running two committee meetings, and complete an outline for a thesis proposal of their major research question. Topics covered will include effective communication skills with science professionals, and creating and managing a research program as part of a team of professionals. This course is run as supervised experiential learning.
Prerequisites: Admission to the M.S. Program in Biology and permission of the instructor.
BIO 630  Advanced Graduate Topics in Cell, Molecular and Developmental Biology  
Credits 1-3   Grading Basis Graded  
Studies in advanced special areas of biology. May be repeated with change in topic or change in subject matter within a topic.
BIO 660  Advanced Graduate Topics in Ecology, Evolution and Organismal Biology  
Credits 1-3   Grading Basis Graded  
Seminar in special areas of biology. May be repeated up to a total of 12 hours with change in subject matter.
BIO 697  Biological Research  
Credits 1-6   Grading Basis Satisfactory/Unsatisfactory  
Laboratory and/or field research will be conducted under the direction of the Graduate Advisory Committee. The course will emphasize the development of research techniques and data collection. Can be repeated for credit. This course is graded on the satisfactory/unsatisfactory (S/U) basis. Hours do not apply toward 30 hours required for graduation.
BIO 698  Comprehensive Continuance  
Credits 1   Grading Basis Comprehensive/Thesis/Dissertation Continuance  
Continued preparation in anticipation of the comprehensive examination. Course may be repeated as needed. A grade of "NC" (no credit) will be automatically entered for continuance hours. Hours do not apply toward 30 hours required for graduation.
BIO 699  Thesis Continuance  
Credits 1   Grading Basis Comprehensive/Thesis/Dissertation Continuance  
Continued study, research and writing in the area of thesis concentration. Course may be repeated as needed. A grade of "NC" (no credit) will be automatically entered for continuance hours. Hours do not apply toward 30 hours required for graduation.
BIO 700  Thesis Research  
Credits 1-6   Grading Basis Satisfactory/Unsatisfactory  
Thesis research to be directed by the Graduate Advisory Committee. This course is graded on a satisfactory/unsatisfactory (S/U) basis.